力学生物学中软物质物理概念的开胃菜

IF 1.7 4区生物学 Q4 CELL BIOLOGY

Development Growth & Differentiation Pub Date : 2023-05-01 DOI:10.1111/dgd.12853

Yuting Lou

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引用次数: 0

摘要

力学感知是细胞对力学的多尺度主动反应，在调节细胞行为和决定组织器官等生物实体的命运中起着不可或缺的作用。在这里，我的目的是给出软物质物理的基本概念的教学说明，帮助理解从组织到蛋白质的生物力学现象。介绍了最新研究的例子来阐述这些概念。在机械生物学领域，生物学家和物理学家也讨论了将物理模型应用于生物学的挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Appetizer on soft matter physics concepts in mechanobiology

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Appetizer on soft matter physics concepts in mechanobiology

Mechanosensing, the active responses of cells to the mechanics on multiple scales, plays an indispensable role in regulating cell behaviors and determining the fate of biological entities such as tissues and organs. Here, I aim to give a pedagogical illustration of the fundamental concepts of soft matter physics that aid in understanding biomechanical phenomena from the scale of tissues to proteins. Examples of up-to-date research are introduced to elaborate these concepts. Challenges in applying physics models to biology have also been discussed for biologists and physicists to meet in the field of mechanobiology.

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来源期刊

Development Growth & Differentiation 生物-发育生物学

CiteScore

4.60

自引率

4.00%

发文量

审稿时长

6 months

期刊介绍： Development Growth & Differentiation (DGD) publishes three types of articles: original, resource, and review papers. Original papers are on any subjects having a context in development, growth, and differentiation processes in animals, plants, and microorganisms, dealing with molecular, genetic, cellular and organismal phenomena including metamorphosis and regeneration, while using experimental, theoretical, and bioinformatic approaches. Papers on other related fields are also welcome, such as stem cell biology, genomics, neuroscience, Evodevo, Ecodevo, and medical science as well as related methodology (new or revised techniques) and bioresources. Resource papers describe a dataset, such as whole genome sequences and expressed sequence tags (ESTs), with some biological insights, which should be valuable for studying the subjects as mentioned above. Submission of review papers is also encouraged, especially those providing a new scope based on the authors’ own study, or a summarization of their study series.