气候变化和相关空气污染对免疫系统的影响导致过敏性疾病和哮喘的机制

IF 7.4 2区 医学 Q1 IMMUNOLOGY
Vanitha Sampath , Juan Aguilera , Mary Prunicki , Kari C. Nadeau
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引用次数: 1

摘要

气候变化被认为是对全球健康的最大威胁。温室气体和全球地表温度上升,导致更频繁、更强烈的热浪和寒潮、野火、洪水、干旱、降雨模式改变、飓风、雷暴、空气污染和风暴。这些极端天气事件对免疫系统有直接和间接的影响,由于接触花粉、霉菌和其他环境污染物而导致过敏性疾病。在这篇综述中,我们将重点关注与气候变化事件引发的过敏和哮喘相关健康风险相关的免疫机制。我们将回顾目前对环境变化介导这些影响的分子和细胞机制的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mechanisms of climate change and related air pollution on the immune system leading to allergic disease and asthma

Climate change is considered the greatest threat to global health. Greenhouse gases as well as global surface temperatures have increased causing more frequent and intense heat and cold waves, wildfires, floods, drought, altered rainfall patterns, hurricanes, thunderstorms, air pollution, and windstorms. These extreme weather events have direct and indirect effects on the immune system, leading to allergic disease due to exposure to pollen, molds, and other environmental pollutants. In this review, we will focus on immune mechanisms associated with allergy and asthma-related health risks induced by climate change events. We will review current understanding of the molecular and cellular mechanisms by which the changing environment mediates these effects.

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来源期刊
Seminars in Immunology
Seminars in Immunology 医学-免疫学
CiteScore
11.40
自引率
1.30%
发文量
50
审稿时长
89 days
期刊介绍: Seminars in Immunology is a specialized review journal that serves as a valuable resource for scientists in the field of immunology. The journal's approach is thematic, with each issue dedicated to a specific topic of significant interest to immunologists. It covers a wide range of research areas, from the molecular and cellular foundations of the immune response to the potential for its manipulation, highlighting recent advancements in these areas. Each thematic issue is curated by a guest editor, who is recognized as an expert in the field internationally. The content of each issue typically includes six to eight authoritative invited reviews, which delve into various aspects of the chosen topic. The goal of these reviews is to provide a comprehensive, coherent, and engaging overview of the subject matter, ensuring that the information is presented in a timely manner to maintain its relevance. The journal's commitment to quality and timeliness is further supported by its inclusion in the Scopus database, which is a leading abstract and citation database of peer-reviewed literature. Being indexed in Scopus helps to ensure that the journal's content is accessible to a broad audience of researchers and professionals in immunology and related fields.
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