Zeina Alabbas, Yamani Tamer, Mhammad Jneidi, Rana Issa
{"title":"侵犯颅骨及皮下组织的轮状硬化性脑膜瘤伴偶发弓形虫病1例。","authors":"Zeina Alabbas, Yamani Tamer, Mhammad Jneidi, Rana Issa","doi":"10.1111/neup.12882","DOIUrl":null,"url":null,"abstract":"<p><p>Whorling-sclerosing meningioma (WSM) is a rare type of meningothelial tumor. Worldwide, only 31 cases have been reported. The diagnosis of this rare meningioma subtype is based principally on microscopic findings, wherein up to 70% of the tumor tissue should be formed by thick whorls of collagen. Notably, there is still disagreement about whether to consider this entity a benign meningioma (grade 1) or a meningioma with higher malignant potential (grade 2 or even grade 3). In fact, the paucity of reported WSM cases and, consequently, the lack of information about their follow up make their diagnosis and treatment challenging. Herein, we document the first case of WSM in Syria in a 75-year-old woman with an incidental finding of Toxoplasma gondii. Although WSM has not been mentioned in the recent World Health Organization classification of central nervous system tumors, it should be recognized to avoid incorrect diagnosis and spare the patients unnecessary radiotherapy and chemotherapy.</p>","PeriodicalId":19204,"journal":{"name":"Neuropathology","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Whorling-sclerosing meningioma invading skull bone and subcutaneous tissue with an incidental toxoplasmosis: A case report.\",\"authors\":\"Zeina Alabbas, Yamani Tamer, Mhammad Jneidi, Rana Issa\",\"doi\":\"10.1111/neup.12882\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Whorling-sclerosing meningioma (WSM) is a rare type of meningothelial tumor. Worldwide, only 31 cases have been reported. The diagnosis of this rare meningioma subtype is based principally on microscopic findings, wherein up to 70% of the tumor tissue should be formed by thick whorls of collagen. Notably, there is still disagreement about whether to consider this entity a benign meningioma (grade 1) or a meningioma with higher malignant potential (grade 2 or even grade 3). In fact, the paucity of reported WSM cases and, consequently, the lack of information about their follow up make their diagnosis and treatment challenging. Herein, we document the first case of WSM in Syria in a 75-year-old woman with an incidental finding of Toxoplasma gondii. Although WSM has not been mentioned in the recent World Health Organization classification of central nervous system tumors, it should be recognized to avoid incorrect diagnosis and spare the patients unnecessary radiotherapy and chemotherapy.</p>\",\"PeriodicalId\":19204,\"journal\":{\"name\":\"Neuropathology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2023-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neuropathology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/neup.12882\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuropathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/neup.12882","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Whorling-sclerosing meningioma invading skull bone and subcutaneous tissue with an incidental toxoplasmosis: A case report.
Whorling-sclerosing meningioma (WSM) is a rare type of meningothelial tumor. Worldwide, only 31 cases have been reported. The diagnosis of this rare meningioma subtype is based principally on microscopic findings, wherein up to 70% of the tumor tissue should be formed by thick whorls of collagen. Notably, there is still disagreement about whether to consider this entity a benign meningioma (grade 1) or a meningioma with higher malignant potential (grade 2 or even grade 3). In fact, the paucity of reported WSM cases and, consequently, the lack of information about their follow up make their diagnosis and treatment challenging. Herein, we document the first case of WSM in Syria in a 75-year-old woman with an incidental finding of Toxoplasma gondii. Although WSM has not been mentioned in the recent World Health Organization classification of central nervous system tumors, it should be recognized to avoid incorrect diagnosis and spare the patients unnecessary radiotherapy and chemotherapy.
期刊介绍:
Neuropathology is an international journal sponsored by the Japanese Society of Neuropathology and publishes peer-reviewed original papers dealing with all aspects of human and experimental neuropathology and related fields of research. The Journal aims to promote the international exchange of results and encourages authors from all countries to submit papers in the following categories: Original Articles, Case Reports, Short Communications, Occasional Reviews, Editorials and Letters to the Editor. All articles are peer-reviewed by at least two researchers expert in the field of the submitted paper.