Basic Phenotyping of Male Fertility from 2019 to 2020 at the Human Sperm Bank of Fudan University.

The aim of this cross-sectional survey was to analyze the semen parameters of volunteers from the Human Sperm Bank of Fudan University, as well as the related factors influencing these parameters. From January 2019 to December 2020, semen parameters from a total of 5214 men were included in this survey. The Kruskal-Wallis test was used to detect differences associated with several independent variables. A total of 5214 volunteers were included. The volunteers were registered in 33 provinces, autonomous regions, municipalities (including Macau and Taiwan) and 294 prefecture-level cities. The average age of volunteers was 27.40 years. Overall, 76.50% of the volunteers had a college education or higher. Volunteers with BMI values of 18.5-23.9 kg/m² accounted for 60.70% of participants. Semen parameters were significantly different according to season, education level, duration of abstinence, age group and BMI. The basic male fertility phenotypes (semen parameters) showed new trends in the study period, and accurate long-term tracking of male semen parameters will help researchers to better understand the changes in male fertility phenotypes (semen).