牛津-阿斯利康COVID-19疫苗接种后新发环状斑块型牛皮癣1例

IF 1.1 Q4 PHARMACOLOGY & PHARMACY

Current drug safety Pub Date : 2023-04-27 DOI:10.2174/1574886317666220613163327

Namrata Chhabra, Anju George C

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引用次数: 1

摘要

背景:实施COVID-19疫苗接种后，已有皮肤病新发或加重的报告病例越来越多。病例描述:一名老年男性在接种牛津-阿斯利康COVID-19疫苗两周后出现全身多个环形鳞状斑块。接种第二剂疫苗后，病变进一步加重。临床和组织病理学特征提示环形斑块型银屑病。结论:我们报道了首例牛津-阿斯利康COVID-19疫苗后新发斑块性银屑病病例，这表明接种COVID疫苗后存在自身免疫再激活的潜在副作用。

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A Case of de novo Annular-plaque Type Psoriasis Following Oxford- AstraZeneca COVID-19 Vaccination.

Background: There have been increasing reported cases of new-onset or aggravation of pre-existing dermatoses after the implementation of COVID-19 vaccination.

Case presentation: An elderly male was presented with multiple annular scaly plaques all over the body two weeks following administration of the first dose of Oxford-AstraZeneca COVID-19 vaccine. The lesions further aggravated after taking the second dose of the vaccine. The clinical and histopathology features were suggestive of annular plaque psoriasis.

Conclusion: We report this first case of de novo plaque psoriasis following the Oxford- AstraZeneca COVID-19 vaccine, and it signifies a potential side effect of autoimmune reactivation after COVID vaccination.

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来源期刊

Current drug safety PHARMACOLOGY & PHARMACY-

CiteScore

2.10

自引率

0.00%

发文量

112

期刊介绍： Current Drug Safety publishes frontier articles on all the latest advances on drug safety. The journal aims to publish the highest quality research articles, reviews and case reports in the field. Topics covered include: adverse effects of individual drugs and drug classes, management of adverse effects, pharmacovigilance and pharmacoepidemiology of new and existing drugs, post-marketing surveillance. The journal is essential reading for all researchers and clinicians involved in drug safety.