血浆激活林格氏乳酸溶液。

IF 3.6 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Free Radical Research Pub Date : 2023-01-01 DOI:10.1080/10715762.2023.2182663

Hiromasa Tanaka, Masaaki Mizuno, Kenji Ishikawa, Camelia Miron, Yasumasa Okazaki, Shinya Toyokuni, Kae Nakamura, Hiroaki Kajiyama, Masaru Hori

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引用次数: 0

摘要

低温等离子体在生命科学中有着广泛的应用。等离子体活化溶液被定义为用LTP照射的溶液，用LTP照射水、介质和林格溶液产生等离子体活化溶液。它们含有LTP、空气和溶液之间反应产生的化合物。活性氧和活性氮(RONS)是等离子体活化溶液的主要成分，近年来的研究表明，等离子体活化的乳酸林格溶液(PAL)中产生了等离子体活化的有机化合物。许多体外和体内研究表明PAL对癌症具有抗肿瘤作用，生化分析揭示了PAL对癌细胞死亡的细胞内分子机制。

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Plasma activated Ringer's lactate solution.

Low-temperature plasma (LTP) has been widely used in life science. Plasma-activated solutions were defined as solutions irradiated with LTP, and water, medium, and Ringer's solutions have been irradiated with LTP to produce plasma-activated solutions. They contain chemical compounds produced by reactions among LTP, air, and solutions. Reactive oxygen and nitrogen species (RONS) are major components in plasma-activated solutions and recent studies revealed that plasma-activated organic compounds are produced in plasma-activated Ringer's lactate solution (PAL). Many in vitro and in vivo studies demonstrated that PAL exhibits anti-tumor effects on cancers, and biochemical analyses revealed intracellular molecular mechanisms of cancer cell death by PAL.

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来源期刊

Free Radical Research 生物-生化与分子生物学

CiteScore

6.70

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： Free Radical Research publishes high-quality research papers, hypotheses and reviews in free radicals and other reactive species in biological, clinical, environmental and other systems; redox signalling; antioxidants, including diet-derived antioxidants and other relevant aspects of human nutrition; and oxidative damage, mechanisms and measurement.