猴痘病毒的热灭活

Q1 Social Sciences

Journal of Biosafety and Biosecurity Pub Date : 2022-12-01 DOI:10.1016/j.jobb.2022.08.001

Christophe Batéjat, Quentin Grassin, Maxence Feher, Damien Hoinard, Jessica Vanhomwegen, Jean-Claude Manuguerra, India Leclercq

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引用次数: 9

摘要

将不同种类的猴痘病毒(MPXV)加入培养基，在不同的温度和不同的时间进行热灭活。结果表明，MPXV在70°C条件下的灭活时间小于5分钟，在60°C条件下的灭活时间小于15分钟，在西非和中非分支的病毒之间没有差异。本研究结果可以帮助实验室工作人员在最佳生物安全条件下操作MPXV并改进其方案。

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Heat inactivation of monkeypox virus

Different kinds of media spiked with monkeypox virus (MPXV) were subjected to heat inactivation at different temperatures for various periods of time. The results showed that MPXV was inactivated in less than 5 min at 70 °C and less than 15 min at 60 °C, with no difference between viruses from the West African and Central African clades. The present findings could help laboratory workers to manipulate MPXV in optimal biosafety conditions and improve their protocols.

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来源期刊

Journal of Biosafety and Biosecurity Social Sciences-Linguistics and Language

CiteScore

6.00

自引率

0.00%

发文量

审稿时长

41 days