颅内表皮样囊肿快速恶性转化1例报告。

IF 1.3 4区医学 Q4 CLINICAL NEUROLOGY

Neuropathology Pub Date : 2023-06-01 DOI:10.1111/neup.12884

Deepti Narasimhaiah, Prakash Nair, Chandran Kesavadas, Rajalakshmi Poyuran

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引用次数: 0

摘要

颅内表皮样囊肿(ECs)发生在沿神经轴的不同位置，占所有颅内肿瘤的近2%。考虑到上皮细胞的发生频率，上皮细胞转化为鳞状细胞癌是罕见的。在这里，我们报告的情况下，39岁的男子谁提出了病变在左小脑桥脑角，并接受了大体全切除相同。组织病理学检查显示为良性EC伴轻度慢性炎症。5个月后，患者在同一部位出现另一个病变，有脑干出血的证据。组织病理学检查显示为中度分化的鳞状细胞癌和先前囊肿的残余，呈层状角蛋白形式，提示EC的恶性转化。

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Rapid malignant transformation of an intracranial epidermoid cyst: Report of a case.

Intracranial epidermoid cysts (ECs) occur at various locations along the neuraxis and account for nearly 2% of all intracranial tumors. Considering the frequency of ECs, transformation of ECs into squamous cell carcinomas is a rare occurrence. Here, we report the case of a 39-year-old man who presented with a lesion in the left cerebellopontine angle and underwent gross total resection for the same. Histopathological examination revealed a benign EC with mild chronic inflammation. Five months later, the patient presented with another lesion at the same location with evidence of brainstem bleed. Histopathological examination revealed a moderately differentiated squamous cell carcinoma and remnants of the previous cyst in the form of lamellated keratin, indicating malignant transformation of the EC.

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来源期刊

Neuropathology 医学-病理学

CiteScore

4.10

自引率

4.30%

发文量

105

审稿时长

6-12 weeks

期刊介绍： Neuropathology is an international journal sponsored by the Japanese Society of Neuropathology and publishes peer-reviewed original papers dealing with all aspects of human and experimental neuropathology and related fields of research. The Journal aims to promote the international exchange of results and encourages authors from all countries to submit papers in the following categories: Original Articles, Case Reports, Short Communications, Occasional Reviews, Editorials and Letters to the Editor. All articles are peer-reviewed by at least two researchers expert in the field of the submitted paper.