阳极对侧 tDCS 可增强患有偏瘫性脑瘫的青少年双侧 CST 兴奋性：简要报告。

IF 1.1 4区医学 Q4 CLINICAL NEUROLOGY

Developmental Neurorehabilitation Pub Date : 2023-04-01 Epub Date: 2023-03-26 DOI:10.1080/17518423.2023.2193626

Rodrigo G Delatorre, Ellen N Sutter, Samuel T Nemanich, Linda E Krach, Gregg Meekins, Timothy Feyma, Bernadette T Gillick

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引用次数: 0

摘要

半身不遂性脑瘫（HCP）通常是由围产期中风引起的一侧肢体无力，其特征是与皮质脊髓束（CST）的改变有关的终生运动障碍。皮质脊髓束重组可能是一种有用的生物标志物，可指导经颅直流电刺激（tDCS）等神经调节干预措施的应用，从而提高康复疗法的效果。我们对一名患有 HCP 和 CST 重组的青少年进行了评估，该青少年在接受阳极对侧 tDCS 治疗后，双上肢的 CST 兴奋性持续升高。研究结果支持进一步研究将有针对性的 tDCS 作为传统神经康复疗法的辅助疗法来治疗上肢功能。

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Anodal Contralesional tDCS Enhances CST Excitability Bilaterally in an Adolescent with Hemiparetic Cerebral Palsy: A Brief Report.

Hemiparetic cerebral palsy (HCP), weakness on one side of the body typically caused by perinatal stroke, is characterized by lifelong motor impairments related to alterations in the corticospinal tract (CST). CST reorganization could be a useful biomarker to guide applications of neuromodulatory interventions, such as transcranial direct current stimulation (tDCS), to improve the effectiveness of rehabilitation therapies. We evaluated an adolescent with HCP and CST reorganization who demonstrated persistent heightened CST excitability in both upper limbs following anodal contralesional tDCS. The results support further investigation of targeted tDCS as an adjuvant therapy to traditional neurorehabilitation for upper limb function.

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来源期刊

Developmental Neurorehabilitation CLINICAL NEUROLOGY-PEDIATRICS

CiteScore

3.10

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Developmental Neurorehabilitation aims to enhance recovery, rehabilitation and education of people with brain injury, neurological disorders, and other developmental, physical and intellectual disabilities. Although there is an emphasis on childhood, developmental disability can be considered from a lifespan perspective. This perspective acknowledges that development occurs throughout a person’s life and thus a range of impairments or diseases can cause a disability that can affect development at any stage of life.