非典型梭形细胞脂肪瘤表现为腹膜后大肿块- 1例报告及文献复习。

IF 0.7 4区医学 Q4 PATHOLOGY

Polish Journal of Pathology Pub Date : 2022-01-01 DOI:10.5114/pjp.2022.125654

Martyna Krupinska, Carmen León, Rocío López Henríquez, Beatriz Esquivel Vázquez, Rosa Nieves Rodríguez Rodríguez, Patricia Marrero Marrero, Luciano Delgado Plasencia, Eduardo Salido

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引用次数: 0

摘要

非典型梭形细胞脂肪瘤(ASCLT)是一种良性肿瘤，表现为不同比例的非典型梭形细胞和脂肪细胞，常表达CD34，包埋在黏液样或胶原基质中。一个重要的特征是持续缺乏MDM2或CDK4扩增。它通常发生在四肢。腹膜后是少见的受累部位。我们报告一个62岁男性的腹膜后ASCLT病例。鉴别诊断ASCLT与其他间充质、梭形细胞和脂肪瘤肿瘤是最佳治疗的关键，并显著影响预后。诊断应根据免疫组织化学和分子检查结果。

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Atypical spindle cell lipomatous tumour presenting as a large retroperitoneal mass - a case report and review of the literature.

Atypical spindle cell lipomatous tumour (ASCLT) is a benign neoplasm that presents a variable proportion of atypical spindle and adipocytic cells, frequently expressing CD34, and embedded in myxoid or collagenous matrix. An important feature is a constant lack of either MDM2 or CDK4 amplification. It typically arises in the extremities. The retroperitoneum is a rare site of involvement. We report a case of a retroperitoneal ASCLT in a 62-year-old male. A differential diagnosis of ASCLT from the other mesenchymal, spindle-cell, and lipomatous tumours is crucial for optimal treatment and significantly influences the prognosis. A diagnosis should be warranted by the immunohistochemistry and molecular findings.

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来源期刊

Polish Journal of Pathology PATHOLOGY-

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Polish Journal of Pathology is an official magazine of the Polish Association of Pathologists and the Polish Branch of the International Academy of Pathology. For the last 18 years of its presence on the market it has published more than 360 original papers and scientific reports, often quoted in reviewed foreign magazines. A new extended Scientific Board of the quarterly magazine comprises people with recognised achievements in pathomorphology and biology, including molecular biology and cytogenetics, as well as clinical oncology. Polish scientists who are working abroad and are international authorities have also been invited. Apart from presenting scientific reports, the magazine will also play a didactic and training role.