{"title":"多发性骨髓瘤伴喉部畸形:一种罕见的发声障碍病因。","authors":"Andrés González Fernández, Maider Berasategui Fuertes, Ignacio Sanhueza Torres, Alba Larrea Ramírez","doi":"10.23938/ASSN.1034","DOIUrl":null,"url":null,"abstract":"<p><p>Plasma cell proliferation leads to the formation of a single tumour (plasmacytoma) or to systemic disease (myeloma). Plasma cell myeloma involving laryngeal cartilage is unusual and clinical manifestations are similar to those of laryngeal carcinoma. We report the case of a 70-year-old man with disphonia after a recent diagnosis of multiple myeloma. Radiological and immunohistochemical studies showed laryngeal involvement. The patient is currently under treatment with lenalidomide, dexamethasone, and bortezomib.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2f/21/assn-46-01-e1034.PMC10208389.pdf","citationCount":"0","resultStr":"{\"title\":\"[Multiple myeloma with laryngeal affectation: an uncommon cause of dysphonia].\",\"authors\":\"Andrés González Fernández, Maider Berasategui Fuertes, Ignacio Sanhueza Torres, Alba Larrea Ramírez\",\"doi\":\"10.23938/ASSN.1034\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Plasma cell proliferation leads to the formation of a single tumour (plasmacytoma) or to systemic disease (myeloma). Plasma cell myeloma involving laryngeal cartilage is unusual and clinical manifestations are similar to those of laryngeal carcinoma. We report the case of a 70-year-old man with disphonia after a recent diagnosis of multiple myeloma. Radiological and immunohistochemical studies showed laryngeal involvement. The patient is currently under treatment with lenalidomide, dexamethasone, and bortezomib.</p>\",\"PeriodicalId\":7775,\"journal\":{\"name\":\"Anales Del Sistema Sanitario De Navarra\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2023-04-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2f/21/assn-46-01-e1034.PMC10208389.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anales Del Sistema Sanitario De Navarra\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.23938/ASSN.1034\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anales Del Sistema Sanitario De Navarra","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.23938/ASSN.1034","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
[Multiple myeloma with laryngeal affectation: an uncommon cause of dysphonia].
Plasma cell proliferation leads to the formation of a single tumour (plasmacytoma) or to systemic disease (myeloma). Plasma cell myeloma involving laryngeal cartilage is unusual and clinical manifestations are similar to those of laryngeal carcinoma. We report the case of a 70-year-old man with disphonia after a recent diagnosis of multiple myeloma. Radiological and immunohistochemical studies showed laryngeal involvement. The patient is currently under treatment with lenalidomide, dexamethasone, and bortezomib.
期刊介绍:
La revista Anales del Sistema Sanitario de Navarra es una revista de contenido médico sanitario de carácter generalista. En ella tienen cabida artículos referidos a temas de salud/enfermedad en general, salud pública, administración y gestión sanitaria y Atención Primaria de salud.