骨髓增生异常综合征的种系易感性。

IF 2.6 4区 医学 Q3 ONCOLOGY
Georgina Gener-Ricos, Yoheved S Gerstein, Danielle Hammond, Courtney D DiNardo
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引用次数: 0

摘要

摘要:虽然骨髓增生异常综合征的种系易感性已经确立,但随着知识的迅速发展,越来越多的遗传性血液系统恶性肿瘤病例被发现。了解遗传性血液系统恶性肿瘤的生物学特征和主要临床表现对于识别和推荐骨髓增生异常综合征患者至关重要,这些患者可能存在遗传易感性,并进行适当的遗传评估。重要的是个性化的遗传咨询以及知情的治疗决定,特别是关于造血干细胞移植相关供体的选择。未来的研究将提高对这些疾病的理解,从而更好地管理受影响的患者及其家属。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Germline Predisposition to Myelodysplastic Syndromes.

Abstract: While germline predisposition to myelodysplastic syndromes is well-established, knowledge has advanced rapidly resulting in more cases of inherited hematologic malignancies being identified. Understanding the biological features and main clinical manifestations of hereditary hematologic malignancies is essential to recognizing and referring patients with myelodysplastic syndrome, who may underlie inherited predisposition, for appropriate genetic evaluation. Importance lies in individualized genetic counseling along with informed treatment decisions, especially with regard to hematopoietic stem cell transplant-related donor selection. Future studies will improve comprehension of these disorders, enabling better management of affected patients and their families.

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来源期刊
Cancer journal
Cancer journal 医学-肿瘤学
CiteScore
3.90
自引率
0.00%
发文量
102
审稿时长
7.5 months
期刊介绍: The Cancer Journal: The Journal of Principles & Practice of Oncology provides an integrated view of modern oncology across all disciplines. The Journal publishes original research and reviews, and keeps readers current on content published in the book Cancer: Principles & Practice of Oncology.
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