Management of multimorbidity.

Multimorbidity is a global challenge with substantial impact on individuals, health-care systems, and society. More than 3 out of 4 consultations in primary care involve multimorbidity and the relationship between the number of chronic conditions and their associated cost is almost exponential. Managing multimorbidity is complex, given the need to address management of individual conditions while incorporating patient preferences. A range of management strategies have been evaluated and the current evidence base includes more than 40 trials. Nevertheless, there is still limited high-quality evidence to guide clinical practice (Table 1).This Editorial highlights management approaches that have potential to improve outcomes for patients with multimorbidity.