急性心肌梗死的诊断:强调心肌肌钙蛋白作为重要的生物标志物。

IF 2.2 4区工程技术 Q3 PHARMACOLOGY & PHARMACY

Bioimpacts Pub Date : 2023-01-01 DOI:10.34172/bi.2023.22023

Ali Pourali, Yadollah Omidi

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引用次数: 1

摘要

分子标记，心肌肌钙蛋白(cTn)是一种复合蛋白，附着在肌动蛋白丝上的原肌球蛋白上。它是一种重要的生物分子，在钙介导的肌原纤维收缩装置的调节中，它的释放是心肌细胞功能障碍的指示，因此是心脏组织缺血现象的开始。快速、准确地分析cTn有助于急性心肌梗死(AMI)的诊断和治疗，电化学生物传感器和微流体装置在这方面具有重要意义。这篇社论旨在强调cTn作为AMI诊断中的重要生物标志物的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers.

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Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers.

The molecular marker, cardiac troponin (cTn) is a complex protein that is attached to tropomyosin on the actin filament. It is an essential biomolecule in terms of the calcium-mediated regulation of the contractile apparatus in myofibrils, the release of which is an indication of the dysfunction of cardiomyocytes and hence the initiation of ischemic phenomena in the heart tissue. Fast and accurate analysis of cTn may help the diagnosis and management of acute myocardial infarction (AMI), for which electrochemical biosensors and microfluidics devices can be of great benefit. This editorial aims to highlight the importance of cTn as vital biomarkers in AMI diagnosis.

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来源期刊

Bioimpacts Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

4.80

自引率

7.70%

发文量

审稿时长

5 weeks

期刊介绍： BioImpacts (BI) is a peer-reviewed multidisciplinary international journal, covering original research articles, reviews, commentaries, hypotheses, methodologies, and visions/reflections dealing with all aspects of biological and biomedical researches at molecular, cellular, functional and translational dimensions.