来自阿拉伯联合酋长国的类风湿关节炎患者缓解和持续缓解的患病率和预测因素:一项为期两年的前瞻性研究

IF 1.7 Q3 RHEUMATOLOGY
Jamal Al-Saleh, Ahlam Almarzooqi, Ahmed A Negm
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引用次数: 0

摘要

目的:评估阿联酋一组类风湿关节炎患者缓解和持续缓解超过12个月的患病率,并探讨这些患者缓解和持续缓解的预测因素。方法:在迪拜医院(2018年1月1日至2019年12月31日)进行的一项为期两年的前瞻性研究纳入了所有在风湿病门诊连续就诊的类风湿关节炎患者。2018年12月简化疾病活动指数≤3.3和/或临床疾病活动指数≤2.8的患者视为缓解,随访至2019年12月。那些在2019年之前保持缓解的人被认为是持续缓解。结果:本研究共对444例患者进行了为期12个月的随访。根据临床疾病活动性指数,RA患者的缓解率为30.4%,根据简化疾病活动性指数为31.1%,根据疾病活动性评分28 (DAS28)缓解标准为50.9%。12个月的持续缓解率从ACR-EULAR的38.3%到DAS28的69.3%不等。男性、疾病持续时间较短、健康评估问卷残疾指数(HAQ分数较低)评估的功能较好以及较高的依从率是持续缓解的预测因素。结论:建立“真实世界”数据和了解持续缓解的当地预测因素是实施及时和适当的患者量身定制策略的主要因素。这些策略包括早期发现、密切监测和加强阿联酋患者的治疗依从性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Prevalence and Predictors of Remission and Sustained Remission in Patients with Rheumatoid Arthritis from the United Arab Emirates: A Two-Year Prospective Study.

Prevalence and Predictors of Remission and Sustained Remission in Patients with Rheumatoid Arthritis from the United Arab Emirates: A Two-Year Prospective Study.

Prevalence and Predictors of Remission and Sustained Remission in Patients with Rheumatoid Arthritis from the United Arab Emirates: A Two-Year Prospective Study.

Aim: To estimate the prevalence of remission and sustained remission for more than 12 months in a cohort of patients with rheumatoid arthritis in the United Arab Emirates and explore predictors of remission and sustained remission in these patients.

Methods: A two-year prospective study conducted in Dubai Hospital (January 1, 2018-December 31, 2019) included all consecutive patients with rheumatoid arthritis attending the rheumatology clinic. Patients with a Simplified Disease Activity Index ≤3.3 and/or Clinical Disease Activity Index ≤2.8 in December 2018 were considered in remission and followed until December 2019. Those who maintained remission through 2019 were considered in sustained remission.

Results: In this study, a total of 444 patients were followed for a 12-months period. The percentage of remission achieved in RA patients was 30.4% according to the Clinical Disease Activity Index, 31.1% according to Simplified Disease Activity Index, and 50.9% according to the Value of Disease Activity Score 28 (DAS28) remission criteria. The 12-months sustained remission rates ranged from 38.3% for the ACR-EULAR to 69.3% for the DAS28. Male gender, shorter disease duration, better functioning as evaluated by the Health Assessment Questionnaire Disability Index (lower HAQ scores), and higher compliance rates are among sustained remission predictors.

Conclusion: Establishing "real-world" data and understanding local predictors to sustained remission is principal for implementing timely and appropriate patient-tailored strategies. These strategies include early detection, close monitoring, and enhancing treatment adherence among UAE patients.

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来源期刊
CiteScore
3.80
自引率
0.00%
发文量
34
审稿时长
16 weeks
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