半月板同种异体移植:手术技术影响临床结果吗?

IF 2.9 2区 医学 Q1 ORTHOPEDICS
Kellen M Worhacz, Thomas R Carter
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引用次数: 1

摘要

综述目的:同种异体半月板移植用于治疗因损伤或半月板切除术导致的半月板缺陷引起的膝关节疼痛。最初被视为一种实验程序,在患者选择和手术技术的改进导致了临床结果的改善,并得到了广泛的接受。我们这篇文章的目的是综述同种异体半月板移植,重点是不同的手术技术及其对结果的影响。最近的发现:关于手术技术的主要争论是使用骨或仅软组织固定半月板角。生物力学和其他基础科学研究表明,当移植物与骨固定时,功能得到改善,挤压减少。然而,一些临床研究显示结果没有差异。长期研究表明,移植物挤压减少可提高成功率,并可能说明骨固定的重要功能。许多临床研究,包括那些有长期结果的研究,已经表明半月板异体移植可以减轻病人的疼痛并改善功能。无论采用何种植骨固定方法,这都是一项具有技术挑战性的手术,具有良好的临床效果。骨固定提供较少的挤压,这与移植物功能的改善和关节恶化率的降低有关。需要进一步的研究来确定其他减少挤压的方法是否能够改善移植物的功能和结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Meniscal Allograft Transplantation: Does Surgical Technique Influence Clinical Outcomes?

Purpose of review: Meniscal allograft transplantation is intended to address painful knees with symptoms that can be attributed to meniscal deficiency through injury or meniscectomy. Initially viewed as an experimental procedure, refinements in patient selection and surgical technique have led to improved clinical outcomes with wider acceptance. Our intention with this paper is to provide a review of meniscal allograft transplantation, with the focus on the different surgical techniques employed and their influence on outcomes.

Recent findings: The main debate regarding surgical technique is using bone or only soft tissue for fixation of the meniscal horns. Biomechanical and other basic science studies show improved function and less extrusion when the grafts are secured with bone. However, several clinical studies show no difference in outcomes. Long-term studies have shown improved success with less graft extrusion and may illustrate the important function of bone fixation. Many clinical studies, including those with long-term outcomes, have shown meniscal allografts can decrease patient pain and improve function. It is a technically challenging procedure with good clinical outcomes regardless of the method of graft fixation. Bone fixation provides less extrusion which is associated with improved graft function and decreased rate of joint deterioration. Further study is needed to determine if other methods to decrease extrusion are able to improve graft function and outcomes.

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来源期刊
CiteScore
7.50
自引率
2.40%
发文量
64
期刊介绍: This journal intends to review the most significant recent developments in the field of musculoskeletal medicine. By providing clear, insightful, balanced contributions by expert world-renowned authors, the journal aims to serve all those involved in the diagnosis, treatment, management, and prevention of musculoskeletal-related conditions. We accomplish this aim by appointing authorities to serve as Section Editors in key subject areas, such as rehabilitation of the knee and hip, sports medicine, trauma, pediatrics, health policy, customization in arthroplasty, and rheumatology. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an Editorial Board of more than 20 diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.
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