神经垂体颗粒细胞瘤,表现为第三脑室肿块。

IF 1.3 4区 医学 Q4 CLINICAL NEUROLOGY
Neuropathology Pub Date : 2023-12-01 Epub Date: 2023-05-05 DOI:10.1111/neup.12907
Gianluca Lopez, Carlo Pescia, Carlo Galli, Manuela Bramerio, Antonella Tosoni, Manuela Nebuloni, Mariarosa Ferrara, Giulio Bertani, Luca Caschera, Fabio Maria Triulzi, Marco Locatelli, Silvia Tabano, Giorgio Alberto Croci
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引用次数: 0

摘要

神经垂体颗粒细胞瘤(GCT)是一种罕见的良性肿瘤,与垂体瘤和梭形细胞癌一样,属于垂体后腺ttf1阳性的低级别肿瘤家族。GCT通常表现为坚实的鞍上肿块,缓慢生长,并随着时间的推移引起压迫症状,偶尔伴有鞍上延伸。它们由多边形单形细胞组成,具有丰富的颗粒状细胞质,在超微结构上充满溶酶体。在这里,我们报告一例GCT表现为第三脑室肿块,放射学上模仿脊索样胶质瘤,伴有GFAP和Annexin-A的异常表达,这使其成为鞍/鞍上和第三脑室肿块的综合诊断方法的一个例子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Granular cell tumor of the neurohypophysis presenting as a third ventricle mass.

Granular cell tumors of the neurohypophysis (GCT) are rare benign neoplasms belonging, along with pituicytoma and spindle cell oncocytoma, to the family of TTF1-positive low-grade neoplasms of the posterior pituitary gland. GCT usually present as a solid sellar mass, slowly growing and causing compressive symptoms over time, occasionally with suprasellar extension. They comprise polygonal monomorphous cells with abundant granular cytoplasm, which is ultrastructurally filled with lysosomes. Here we report the case of a GCT presenting as a third ventricle mass, radiologically mimicking chordoid glioma, with aberrant expression of GFAP and Annexin-A, which lends itself as an example of an integrated diagnostic approach to sellar/suprasellar and third ventricle masses.

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来源期刊
Neuropathology
Neuropathology 医学-病理学
CiteScore
4.10
自引率
4.30%
发文量
105
审稿时长
6-12 weeks
期刊介绍: Neuropathology is an international journal sponsored by the Japanese Society of Neuropathology and publishes peer-reviewed original papers dealing with all aspects of human and experimental neuropathology and related fields of research. The Journal aims to promote the international exchange of results and encourages authors from all countries to submit papers in the following categories: Original Articles, Case Reports, Short Communications, Occasional Reviews, Editorials and Letters to the Editor. All articles are peer-reviewed by at least two researchers expert in the field of the submitted paper.
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