[妊娠期黄体生成素过度反应和一例偶然发现的卵巢FIGO IIIB边界肿瘤——诊断、治疗和文献综述]。

IF 0.7 4区 医学 Q4 OBSTETRICS & GYNECOLOGY
Zeitschrift fur Geburtshilfe und Neonatologie Pub Date : 2023-10-01 Epub Date: 2023-05-02 DOI:10.1055/a-2065-0231
Franziska Mergel, Fabienne Schochter, Nikolaus DeGregorio, Wolfgang Janni, Frank Reister, Ulrike Friebe-Hofmann, Beate Hüner
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引用次数: 0

摘要

附件肿块影响2-10%的妊娠。妊娠早期发病率最高,为1-6%,自发缓解率高。其中2%为恶性肿瘤或交界性肿瘤。一种罕见的妊娠期附件良性肿块是反应性黄体增生,其特征是双侧多囊卵巢,在妊娠晚期经常发生。临床症状包括母体高雄激素血症伴男性化、充血、非特异性腹痛或甲状腺功能亢进和高血糖的实验室检查结果。由于产后完全自发缓解,黄体生成素过度反应不需要治疗,但在妊娠期通常通过手术治疗。在我们的病例中,我们报告了一例妊娠第31周的首次妊娠,有症状的25厘米多囊,部分固体肿块。在产前皮质类固醇治疗后,怀疑恶性肿瘤,进行了剖腹探查和右附件切除术。组织学显示黄体生成素反应过度,并偶然发现卵巢浆液性交界性肿瘤(图IIIB)。在妊娠33周时,观察到病理性CTG,并通过再次纵向剖腹手术进行紧急二次剖腹产。产后完成手术后没有发现进一步的肿瘤细胞。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Hyperreactio Luteinalis and an Incidentally Detected FIGO IIIB Borderline Tumor of the Ovary in Pregnancy - Diagnostic, Therapy and Review of Literature].

Adnexal masses affect 2-10% of all pregnancies. The highest incidence of 1-6% can be seen in the first trimester, with a high rate of spontaneous remission. Two percent of these masses are malignant neoplasms or borderline tumors. A rare benign mass of the adnexa in pregnancy is hyperreactio luteinalis characterised by bilateral, multicystic ovaries with a frequent occurrence in the 3rd trimester. Clinical signs include maternal hyperandrogenaemia with virilisation, hyperemesis, nonspecific abdominal pain or laboratory findings of hyperthyroidism and elevated ß-HCG. Hyperreactio luteinalis does not require therapy due to complete spontaneous remission postpartum, but is often treated surgically in graviditate. In our case we report a first-time gravida in the 31st week of pregnancy with a symptomatic 25-cm multicystic, partly solid mass. After antenatal corticosteroid therapy, an exploratory laparotomy with right adnexectomy was performed on suspicion of malignancy. Histology revealed a hyperreactio luteinalis with an incidental finding of a serous borderline tumor of the ovary (FIGO IIIB). At 33 weeks of gestation, a pathological CTG was observed, and an urgent secondary caesarean section by re-longitudinal laparotomy was performed. Postpartum completion surgery revealed no further neoplastic cells.

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来源期刊
Zeitschrift fur Geburtshilfe und Neonatologie
Zeitschrift fur Geburtshilfe und Neonatologie OBSTETRICS & GYNECOLOGY-PEDIATRICS
CiteScore
1.10
自引率
0.00%
发文量
166
审稿时长
>12 weeks
期刊介绍: Gynäkologen, Geburtshelfer, Hebammen, Neonatologen, Pädiater
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