{"title":"Janus纳米粒子生物传感平台的最新进展。","authors":"Srushti Karadkar, Abhishekh Tiwari, Atul Changdev Chaskar","doi":"10.1007/s40089-022-00385-x","DOIUrl":null,"url":null,"abstract":"<p><p>Nanoparticles have aided in the development of nano-based sensors for diagnostic applications. However, use of nanoparticles in the development of sensing devices for multiple analyte detection is constrained due to their inability to detect several analytes with a single type of nanoparticle. The term \"Janus particle\" refers to micro or nanoscale particles that have been divided into sections or compartments, each of which has a distinct set of chemical or physical properties, producing multifunctional particles endowed with distinctive qualities. Furthermore, Janus particles have the ability to perform multiple functions within a single particle at the same time, with no interference from adjacent sections. This review focuses on the use of Janus particles in the fabrication of biosensors as well as in the investigation of various properties endowed by these Janus particles for their use as biosensors. It also discusses the various types of Janus particle-based biosensors that are currently available. Finally, the limitations of Janus particles in sensor technologies and their future scope have been discussed.</p><p><strong>Graphical abstract: </strong></p>","PeriodicalId":14440,"journal":{"name":"International Nano Letters","volume":"13 2","pages":"93-115"},"PeriodicalIF":4.1000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676883/pdf/","citationCount":"2","resultStr":"{\"title\":\"Recent advancements in Janus nanoparticle-based biosensing platforms.\",\"authors\":\"Srushti Karadkar, Abhishekh Tiwari, Atul Changdev Chaskar\",\"doi\":\"10.1007/s40089-022-00385-x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Nanoparticles have aided in the development of nano-based sensors for diagnostic applications. However, use of nanoparticles in the development of sensing devices for multiple analyte detection is constrained due to their inability to detect several analytes with a single type of nanoparticle. The term \\\"Janus particle\\\" refers to micro or nanoscale particles that have been divided into sections or compartments, each of which has a distinct set of chemical or physical properties, producing multifunctional particles endowed with distinctive qualities. Furthermore, Janus particles have the ability to perform multiple functions within a single particle at the same time, with no interference from adjacent sections. This review focuses on the use of Janus particles in the fabrication of biosensors as well as in the investigation of various properties endowed by these Janus particles for their use as biosensors. It also discusses the various types of Janus particle-based biosensors that are currently available. Finally, the limitations of Janus particles in sensor technologies and their future scope have been discussed.</p><p><strong>Graphical abstract: </strong></p>\",\"PeriodicalId\":14440,\"journal\":{\"name\":\"International Nano Letters\",\"volume\":\"13 2\",\"pages\":\"93-115\"},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9676883/pdf/\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Nano Letters\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s40089-022-00385-x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"NANOSCIENCE & NANOTECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Nano Letters","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s40089-022-00385-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NANOSCIENCE & NANOTECHNOLOGY","Score":null,"Total":0}
Recent advancements in Janus nanoparticle-based biosensing platforms.
Nanoparticles have aided in the development of nano-based sensors for diagnostic applications. However, use of nanoparticles in the development of sensing devices for multiple analyte detection is constrained due to their inability to detect several analytes with a single type of nanoparticle. The term "Janus particle" refers to micro or nanoscale particles that have been divided into sections or compartments, each of which has a distinct set of chemical or physical properties, producing multifunctional particles endowed with distinctive qualities. Furthermore, Janus particles have the ability to perform multiple functions within a single particle at the same time, with no interference from adjacent sections. This review focuses on the use of Janus particles in the fabrication of biosensors as well as in the investigation of various properties endowed by these Janus particles for their use as biosensors. It also discusses the various types of Janus particle-based biosensors that are currently available. Finally, the limitations of Janus particles in sensor technologies and their future scope have been discussed.
期刊介绍：
The overall aim of the International Nano Letters is to bring science and applications together on nanoscale and nanostructured materials with emphasis on synthesis, processing, characterization, and applications of materials containing true nanosize dimensions or nanostructures that enable novel/enhanced properties or functions. It is directed at both academic researchers and practicing engineers. International Nano Letters is covering fundamental and applied research in all disciplines of science, engineering and medicine. INL publishes all aspects of nanoscale science and technology dealing with materials synthesis, processing, nanofabrication, nano-polymer, nano-catalyst, nano-particles, nano-probes, spectroscopy, properties, biological systems, nano-structures, theory and computation, nano-electronics, nano-optics, nano-mechanics, nano-devices, nano-detection, nano-biotechnology, nano-medicine, nano-drug delivery, nano-toxicology. All articles should emphasize original results relating to experimental, theoretical, computational, and/or applications of nanomaterials. All contributions will be peer reviewed.
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