{"title":"无神经系统疾病老年男性逼尿肌活动不足的临床特征","authors":"Keisuke Kiba, Yasunori Akashi, Yutaka Yamamoto, Akihide Hirayama, Kiyohide Fujimoto, Hirotsugu Uemura","doi":"10.1111/luts.12424","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objectives</h3>\n \n <p>To investigate the clinical features of detrusor underactivity (DU) in elderly men without neurological disorders.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>A total of 336 men aged ≥50 years without neurogenic disorders who underwent pressure flow studies and who had DU or bladder outlet obstruction (BOO) were reviewed retrospectively. According to the bladder contractility index (BCI) and the BOO index (BOOI), the subjects were classified into the following three groups: (a) pure DU group, BCI < 100 and BOOI < 40; (b) DU + BOO group, BCI < 100 and BOOI ≥ 40; and (c) pure BOO group, BCI ≥ 100 and BOOI ≥ 40. Subjective and objective parameters were compared among the three groups, and the predictors for pure DU were evaluated by multivariate analysis.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Of the 336 patients, 205 who met the study criteria were included in the analysis: 63 (30.7%) with pure DU, 48 (23.4%) with DU + BOO, and 94 (45.9%) with pure BOO. The proportion of the pure DU group increased with increasing age. Prostate volume was the lowest in the pure DU group. Frequency, urgency on the International Prostate Symptom Score (IPSS), and the IPSS storage subscore were the lowest in the pure DU group. Multivariate analysis showed that age (odds ratio [OR] 1.114 [95% CI, 1.032-1.203], <i>P</i> = .005), prostate volume (OR 0.968 [95% CI, 0.949-0.987], <i>P</i> = .001), and urgency (OR 0.623 [95% CI, 0.431-0.900], <i>P</i> = .012) were predictors of pure DU.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Older age, smaller prostate volume, and less urgency may be clinical features of pure DU.</p>\n </section>\n </div>","PeriodicalId":18028,"journal":{"name":"LUTS: Lower Urinary Tract Symptoms","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2022-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Clinical features of detrusor underactivity in elderly men without neurological disorders\",\"authors\":\"Keisuke Kiba, Yasunori Akashi, Yutaka Yamamoto, Akihide Hirayama, Kiyohide Fujimoto, Hirotsugu Uemura\",\"doi\":\"10.1111/luts.12424\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objectives</h3>\\n \\n <p>To investigate the clinical features of detrusor underactivity (DU) in elderly men without neurological disorders.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>A total of 336 men aged ≥50 years without neurogenic disorders who underwent pressure flow studies and who had DU or bladder outlet obstruction (BOO) were reviewed retrospectively. According to the bladder contractility index (BCI) and the BOO index (BOOI), the subjects were classified into the following three groups: (a) pure DU group, BCI < 100 and BOOI < 40; (b) DU + BOO group, BCI < 100 and BOOI ≥ 40; and (c) pure BOO group, BCI ≥ 100 and BOOI ≥ 40. Subjective and objective parameters were compared among the three groups, and the predictors for pure DU were evaluated by multivariate analysis.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Of the 336 patients, 205 who met the study criteria were included in the analysis: 63 (30.7%) with pure DU, 48 (23.4%) with DU + BOO, and 94 (45.9%) with pure BOO. The proportion of the pure DU group increased with increasing age. Prostate volume was the lowest in the pure DU group. Frequency, urgency on the International Prostate Symptom Score (IPSS), and the IPSS storage subscore were the lowest in the pure DU group. Multivariate analysis showed that age (odds ratio [OR] 1.114 [95% CI, 1.032-1.203], <i>P</i> = .005), prostate volume (OR 0.968 [95% CI, 0.949-0.987], <i>P</i> = .001), and urgency (OR 0.623 [95% CI, 0.431-0.900], <i>P</i> = .012) were predictors of pure DU.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Older age, smaller prostate volume, and less urgency may be clinical features of pure DU.</p>\\n </section>\\n </div>\",\"PeriodicalId\":18028,\"journal\":{\"name\":\"LUTS: Lower Urinary Tract Symptoms\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2022-01-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"LUTS: Lower Urinary Tract Symptoms\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/luts.12424\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"LUTS: Lower Urinary Tract Symptoms","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/luts.12424","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 3
摘要
目的探讨无神经系统疾病的老年男性逼尿肌活动不足的临床特点。方法回顾性分析336例年龄≥50岁、无神经源性疾病、行压力血流检查且患有DU或膀胱出口梗阻(BOO)的男性患者。根据膀胱收缩指数(BCI)和BOO指数(BOOI)将受试者分为3组:(a)纯DU组,BCI < 100, BOOI < 40;(b) DU + BOO组,BCI < 100, BOOI≥40;(c)纯BOO组,BCI≥100,BOOI≥40。比较三组患者的主客观指标,并通过多因素分析评价纯DU的预测因素。结果在336例患者中,205例符合研究标准的患者纳入分析:63例(30.7%)为纯DU, 48例(23.4%)为DU + BOO, 94例(45.9%)为纯BOO。纯DU组的比例随着年龄的增长而增加。纯DU组前列腺体积最小。国际前列腺症状评分(IPSS)的频率、紧迫性和IPSS储存亚评分在纯DU组中最低。多因素分析显示,年龄(比值比[OR] 1.114 [95% CI, 1.032-1.203], P = 0.005)、前列腺体积(比值比[OR] 0.968 [95% CI, 0.949-0.987], P = 0.001)和急症(比值比[OR] 0.623 [95% CI, 0.431-0.900], P = 0.012)是单纯DU的预测因素。结论年龄较大、前列腺体积较小、急迫性较差可能是单纯DU的临床特征。
Clinical features of detrusor underactivity in elderly men without neurological disorders
Objectives
To investigate the clinical features of detrusor underactivity (DU) in elderly men without neurological disorders.
Methods
A total of 336 men aged ≥50 years without neurogenic disorders who underwent pressure flow studies and who had DU or bladder outlet obstruction (BOO) were reviewed retrospectively. According to the bladder contractility index (BCI) and the BOO index (BOOI), the subjects were classified into the following three groups: (a) pure DU group, BCI < 100 and BOOI < 40; (b) DU + BOO group, BCI < 100 and BOOI ≥ 40; and (c) pure BOO group, BCI ≥ 100 and BOOI ≥ 40. Subjective and objective parameters were compared among the three groups, and the predictors for pure DU were evaluated by multivariate analysis.
Results
Of the 336 patients, 205 who met the study criteria were included in the analysis: 63 (30.7%) with pure DU, 48 (23.4%) with DU + BOO, and 94 (45.9%) with pure BOO. The proportion of the pure DU group increased with increasing age. Prostate volume was the lowest in the pure DU group. Frequency, urgency on the International Prostate Symptom Score (IPSS), and the IPSS storage subscore were the lowest in the pure DU group. Multivariate analysis showed that age (odds ratio [OR] 1.114 [95% CI, 1.032-1.203], P = .005), prostate volume (OR 0.968 [95% CI, 0.949-0.987], P = .001), and urgency (OR 0.623 [95% CI, 0.431-0.900], P = .012) were predictors of pure DU.
Conclusion
Older age, smaller prostate volume, and less urgency may be clinical features of pure DU.
期刊介绍:
LUTS is designed for the timely communication of peer-reviewed studies which provides new clinical and basic science information to physicians and researchers in the field of neurourology, urodynamics and urogynecology. Contributions are reviewed and selected by a group of distinguished referees from around the world, some of whom constitute the journal''s Editorial Board. The journal covers both basic and clinical research on lower urinary tract dysfunctions (LUTD), such as overactive bladder (OAB), detrusor underactivity, benign prostatic hyperplasia (BPH), bladder outlet obstruction (BOO), urinary incontinence, pelvic organ prolapse (POP), painful bladder syndrome (PBS), as well as on other relevant conditions. Case reports are published only if new findings are provided.
LUTS is an official journal of the Japanese Continence Society, the Korean Continence Society, and the Taiwanese Continence Society. Submission of papers from all countries are welcome. LUTS has been accepted into Science Citation Index Expanded (SCIE) with a 2011 Impact Factor.