妊娠早期感染SARS-COV-2后VACTERL相关性的产前诊断

IF 1.3 4区医学 Q3 PEDIATRICS

Congenital Anomalies Pub Date : 2022-12-14 DOI:10.1111/cga.12503

Angel Chimenea, Lutgardo García-Díaz, Ana María Calderón, Guillermo Antiñolo

{"title":"妊娠早期感染SARS-COV-2后VACTERL相关性的产前诊断","authors":"Angel Chimenea, Lutgardo García-Díaz, Ana María Calderón, Guillermo Antiñolo","doi":"10.1111/cga.12503","DOIUrl":null,"url":null,"abstract":"<p>Organogenesis is a period of fetal development with a special vulnerability to biological and environmental agents. There are some viral infections whose transmission in the first trimester carries a significant risk for the development of congenital anomalies. Although the possibility of vertical transmission of SARS-CoV-2 during pregnancy has been demonstrated, there are no studies evaluating the impact of SARS-CoV-2 infection in the first trimester and its possible association with congenital anomalies. In this communication, we present the case of a pregnant woman with early SARS-CoV-2 infection, prenatally diagnosed with fetal VACTERL association by mid-trimester ultrasound. Further studies are needed to determine the causal association.</p>","PeriodicalId":10626,"journal":{"name":"Congenital Anomalies","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877562/pdf/CGA-9999-0.pdf","citationCount":"1","resultStr":"{\"title\":\"Prenatal diagnosis of VACTERL association after early-first trimester SARS-COV-2 infection\",\"authors\":\"Angel Chimenea, Lutgardo García-Díaz, Ana María Calderón, Guillermo Antiñolo\",\"doi\":\"10.1111/cga.12503\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Organogenesis is a period of fetal development with a special vulnerability to biological and environmental agents. There are some viral infections whose transmission in the first trimester carries a significant risk for the development of congenital anomalies. Although the possibility of vertical transmission of SARS-CoV-2 during pregnancy has been demonstrated, there are no studies evaluating the impact of SARS-CoV-2 infection in the first trimester and its possible association with congenital anomalies. In this communication, we present the case of a pregnant woman with early SARS-CoV-2 infection, prenatally diagnosed with fetal VACTERL association by mid-trimester ultrasound. Further studies are needed to determine the causal association.</p>\",\"PeriodicalId\":10626,\"journal\":{\"name\":\"Congenital Anomalies\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2022-12-14\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877562/pdf/CGA-9999-0.pdf\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Congenital Anomalies\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/cga.12503\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Congenital Anomalies","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/cga.12503","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PEDIATRICS","Score":null,"Total":0}

引用次数: 1

摘要

器官发生是胎儿发育的一个阶段，对生物和环境因素具有特殊的脆弱性。有一些病毒感染，其传播在前三个月有很大的风险发展的先天性异常。尽管已证实妊娠期间SARS-CoV-2垂直传播的可能性，但尚未有研究评估SARS-CoV-2感染在妊娠早期的影响及其与先天性异常的可能关联。在这篇通讯中，我们报告了一例早期感染SARS-CoV-2的孕妇，产前通过中期超声诊断为胎儿VACTERL关联。需要进一步的研究来确定因果关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Prenatal diagnosis of VACTERL association after early-first trimester SARS-COV-2 infection

Organogenesis is a period of fetal development with a special vulnerability to biological and environmental agents. There are some viral infections whose transmission in the first trimester carries a significant risk for the development of congenital anomalies. Although the possibility of vertical transmission of SARS-CoV-2 during pregnancy has been demonstrated, there are no studies evaluating the impact of SARS-CoV-2 infection in the first trimester and its possible association with congenital anomalies. In this communication, we present the case of a pregnant woman with early SARS-CoV-2 infection, prenatally diagnosed with fetal VACTERL association by mid-trimester ultrasound. Further studies are needed to determine the causal association.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Congenital Anomalies PEDIATRICS-

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Congenital Anomalies is the official English language journal of the Japanese Teratology Society, and publishes original articles in laboratory as well as clinical research in all areas of abnormal development and related fields, from all over the world. Although contributions by members of the teratology societies affiliated with The International Federation of Teratology Societies are given priority, contributions from non-members are welcomed.