1988-1997年和2008-2017年青壮年首次缺血性卒中的比较

IF 2.6 Q2 PERIPHERAL VASCULAR DISEASE

Vascular Health and Risk Management Pub Date : 2023-01-01 DOI:10.2147/VHRM.S398127

Mohamad Farah, Halvor Næss, Ulrike Waje-Andreassen, Beenish Nawaz, Annette Fromm

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引用次数: 0

摘要

目的:比较1988-1997年和2008-2017年挪威霍达兰县15-49岁年轻人首次急性脑梗死的发病率、病因和传统危险因素。方法:对1988-1997年霍达兰县医院登记的青年急性脑梗死病例进行计算机回顾性分析。2008-2017年生活在卑尔根地区的年轻急性脑梗死患者被前瞻性地纳入豪克兰大学医院的数据库。记录传统危险因素、病因及出院时修正Rankin量表评分。结果:1988-1997年急性脑梗死粗平均发病率为11.4 / 10万/年，2008-2017年为13.2 / 10万/年(P=0.04)。在2008-2017年队列中，既往心肌梗死、心绞痛和血脂异常的患病率较低(均为p)。结论:1988-1997年至2008-2017年，霍达兰县青壮年急性脑梗死的发病率有所上升。动脉粥样硬化在2008-2017年队列中较少见。

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Comparison Between First-Ever Ischemic Stroke in Young Adults in 1988-1997 and 2008-2017.

Aim: To compare incidence of first-ever acute cerebral infarction, etiology and traditional risk factors in young adults 15-49 years in 1988-1997 and 2008-2017 in Hordaland County, Norway.

Methods: Case-finding of young adults with acute cerebral infarction in 1988-1997 was done retrospectively by computer research from hospital registries in Hordaland County. Young adults with acute cerebral infarction living in the Bergen region in 2008-2017 were prospectively included in a database at Haukeland University Hospital. Traditional risk factors, etiology and modified Rankin scale score on discharge were registered.

Results: Crude average incidence of acute cerebral infarction was 11.4 per 100.000 per year in 1988-1997 and 13.2 per 100.000 per year in 2008-2017 (P=0.04). The prevalence of prior myocardial infarction, angina pectoris, and dyslipidemia were lower in the 2008-2017 cohort (all P<0.05). Atherosclerosis was less common in the 2008-2017 cohort (P<0.001).

Conclusion: The observed incidence of acute cerebral infarction in young adults increased from 1988-1997 to 2008-2017 in Hordaland County. Atherosclerosis was less common in the 2008-2017 cohort.

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来源期刊

Vascular Health and Risk Management PERIPHERAL VASCULAR DISEASE-

CiteScore

4.20

自引率

3.40%

发文量

109

审稿时长

16 weeks

期刊介绍： An international, peer-reviewed journal of therapeutics and risk management, focusing on concise rapid reporting of clinical studies on the processes involved in the maintenance of vascular health; the monitoring, prevention, and treatment of vascular disease and its sequelae; and the involvement of metabolic disorders, particularly diabetes. In addition, the journal will also seek to define drug usage in terms of ultimate uptake and acceptance by the patient and healthcare professional.