伴有淀粉样蛋白沉积的眼眶 MALT 淋巴瘤。

Pub Date : 2024-08-01 Epub Date: 2023-05-01 DOI:10.1080/01676830.2023.2203750
Carleigh N Bruce, Steven H Kroft, Gerald J Harris
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引用次数: 0

摘要

MALT淋巴瘤是一种常见的眼眶肿瘤,原发性淀粉样变性经常被发现是一种独立的眼眶病变。伴有淀粉样蛋白沉积的眼眶MALT淋巴瘤非常罕见,此前仅发表过12例。我们描述了一名33岁的男性患者,他是迄今为止报告的最年轻的患者,其右眼眶前部上鼻象限有一肿块。病理结果显示,粘膜相关淋巴组织中的结节外边缘区淋巴瘤伴有淀粉样沉积。全身检查未发现淋巴瘤或淀粉样变性的其他部位。患者接受了局部照射,随后手术切除了残留肿块。发现了持续存在的淋巴瘤,并用利妥昔单抗进行了治疗。
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Orbital MALT lymphoma with amyloid deposition.

MALT lymphoma is a commonly encountered orbital tumor, and primary amyloidosis is frequently found to be an independent orbital lesion. Orbital MALT lymphoma with associated amyloid deposition is considered rare, with only 12 cases previously published. We describe a 33-year-old man, the youngest patient reported to-date, with a mass in the superonasal quadrant of the right anterior orbit. Pathology demonstrated extranodal marginal zone lymphoma in mucosa-associated lymphoid tissue with associated amyloid deposition. Systemic work-up revealed no other site of either lymphoma or amyloidosis. The patient underwent local irradiation and subsequent surgical resection of the residual mass. Persistent lymphoma was found and treated with rituximab.

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