血液透析患者的慢性肾病相关性瘙痒:干燥和局部治疗

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-02-22 DOI:10.1111/hdi.13071

Arum Krismi, Retno Danarti, Ida I. Dewa Putu Pramantara Setiabudi, Yohanes W. Wirohadidjojo

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引用次数: 0

摘要

慢性肾脏疾病相关性瘙痒(CKD- ap)是慢性肾脏疾病患者常见且令人痛苦的症状，也是肾病学家和皮肤科医生面临的一个难题。最近的结果显示病理生理学的多因素性质，治疗试验仅在某些亚组患者中成功。临床表现多种多样，干燥是最常见的皮肤病表现，与CKD-aP的强度相关。更好地了解CKD-aP干枯的病理生理，适当的局部治疗可以纠正干枯，降低CKD-aP的强度，提高患者的生活质量。

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Chronic kidney disease-associated pruritus in patients undergoing hemodialysis: Xerosis and topical therapy

Chronic kidney disease-associated pruritus (CKD-aP) is a common and distressing symptom for patients with CKD and a difficult challenge for nephrologists and dermatologists. Recent results showed the multifactorial nature of the pathophysiology, and therapeutic trials were only successful in certain subsets of patients. The clinical manifestations are varied, with xerosis being the most common dermatological manifestation and correlated with the intensity of CKD-aP. A better understanding of the pathophysiology of xerosis in CKD-aP and appropriate topical treatment could correct xerosis to reduce the intensity of CKD-aP and improve the patient's quality of life.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.