慢性化脓性中耳炎(CSOM)患者的听力学分析与微生物学结果的映射:一个被忽视的临床表现。

IF 6.6 2区 医学 Q1 MEDICAL LABORATORY TECHNOLOGY
Shefali Dhingra, Dharam Vir, Jaimanti Bakshi, Praveen Rishi
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引用次数: 2

摘要

中耳炎(OM)是与中耳炎症相关的一系列病症的总称。慢性化脓性中耳炎(CSOM)是一种慢性中耳炎,其特点是长期中耳感染,伴有耳膜穿孔和耳漏。与此相关的最常见的结果是感染个体的获得性听力障碍,最终影响他们的认知和学业发展。临床上,慢性中耳炎被认为是急性中耳炎(AOM)反复发作的后遗症。铜绿假单胞菌和金黄色葡萄球菌是这些患者的主要致病菌株。然而,随着这些病原体中抗生素耐药性的出现,对这种情况的充分评估和治疗变得更加困难。该病还被认为是一种被忽视的热带临床表现,在学龄儿童中发病率很高,特别是在贫穷或弱势国家。此外,未经治疗的病例会导致各种危及生命的并发症,从而使情况进一步恶化。因此,有效的治疗和手术策略,以及加强听力保健算法,以及为先进的临床研究发现新的动物模型,可以共同帮助对抗这种疾病。在这方面,将听力学分析与CSOM患者的微生物学发现相结合,可能有助于阐明有利于特定病原体生长的频率。了解这种潜在的相关性可以支持及时发现感染,这被认为是其管理的新兴方法之一。除了这些策略之外,在人们中建立真正的意识也可以通过促进早期识别、预防和治疗来帮助减轻这种病理状况。本文综述了与CSOM相关的发病率、发病机制、调查、并发症和可用的治疗方式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mapping of audiometric analysis with microbiological findings in patients with chronic suppurative otitis media (CSOM): a neglected clinical manifestation.

Otitis media (OM) is an umbrella term for a number of conditions associated with middle ear inflammation. Chronic suppurative otitis media (CSOM), a type of OM, is characterized by long-term middle ear infection with perforated ear drum and otorrhea. The most common outcome associated with it is acquired hearing impairment in infected individuals which ultimately affects their cognitive and scholastic developments. Clinically, CSOM is thought to be a sequel of re-occurring episodes of Acute otitis media (AOM). Pseudomonas aeruginosa and Staphylococcus aureus are found to be the predominant pathogenic isolates in these patients. However, with the emergence of antibiotic resistance amongst these pathogens, the adequate evaluation and treatment of this condition has become more problematic. The disease has also been recognized as one of the neglected tropical clinical manifestations with high prevalence in school-age children, especially in poor or underprivileged countries. Moreover, untreated cases have further worsened the situation by contributing to various life-threatening complications. Thus, effective treatment and surgical strategies, as well as strengthening of hearing care algorithms along with the discovery of novel animal models for advanced clinical research, can jointly help to fight this disease. In this regard, mapping of the audiological analysis with microbiological findings in CSOM patients may help elucidate the frequency that favors growth of specific pathogens. Knowledge about this potential correlation can then support timely detection of the infection, which is perceived as one of the emerging approaches for its management. In addition to these strategies, creating a true sense of awareness among people can also help mitigate this pathological condition by facilitating early identification, prevention, and treatment. This review discusses the incidence, pathogenesis, investigations, complications, and available treatment modalities associated with CSOM.

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来源期刊
CiteScore
20.00
自引率
0.00%
发文量
25
审稿时长
>12 weeks
期刊介绍: Critical Reviews in Clinical Laboratory Sciences publishes comprehensive and high quality review articles in all areas of clinical laboratory science, including clinical biochemistry, hematology, microbiology, pathology, transfusion medicine, genetics, immunology and molecular diagnostics. The reviews critically evaluate the status of current issues in the selected areas, with a focus on clinical laboratory diagnostics and latest advances. The adjective “critical” implies a balanced synthesis of results and conclusions that are frequently contradictory and controversial.
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