健康受试者乳头周围和乳头旁脉络膜厚度的相关性。

Q3 Medicine
Dong Hwan Son, Jinho Lee, Jeong-Ah Kim
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引用次数: 1

摘要

目的:评价两种测量视神经头周围脉络膜厚度的方法的相关性。方法:我们进行了横断面研究。纳入62名健康受试者的62只眼睛。利用光谱域光学相干断层扫描技术,获得了一张直径为3.5 mm的乳头周围圆形扫描和24张以布鲁氏膜开口(BMO)为中心的径向b扫描图像。分别采用圆形和径向b扫描图像测量乳头周围脉络膜厚度(PPCT)和乳头旁脉络膜厚度(JPCT)。分析了两种方法测量值的相关性和一致性。评估与PPCT和JPCT相关的因素,以及两种方法测量值的差异。结果:共纳入62名健康受试者的62只眼。平均PPCT为165.2±50.1 μm, JPCT为139.7±39.2 μm。线性回归分析显示两种测量结果之间有很强的相关性(PPCT vs. JPCT, r²= 0.900,p < 0.001)。PPCT和JPCT测量结果在全球和所有六个部门显示出良好的一致性(类内相关系数>0.900)。Bland-Altman图显示两种方法的一致性较好,系统偏差为17.9 μm, 95%的一致性限(±1.96标准差)为-9.6 ~ 60.5。多因素回归分析中,BMO面积(β = -11.87, p = 0.002)是唯一与PPCT与JPCT差异显著相关的因素,两者呈负相关。随着BMO面积的减小,PPCT与JPCT测量值的差异(PPCT - JPCT)呈发散趋势。结论:两种测量ONH周围脉络膜厚度的方法具有良好的相关性。然而,乳头周围的脉络膜通常比乳头旁的更厚,尤其是在BMO面积小的眼睛。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The Correlation of Peripapillary and Juxtapapillary Choroidal Thickness in Healthy Subjects.

The Correlation of Peripapillary and Juxtapapillary Choroidal Thickness in Healthy Subjects.

The Correlation of Peripapillary and Juxtapapillary Choroidal Thickness in Healthy Subjects.

The Correlation of Peripapillary and Juxtapapillary Choroidal Thickness in Healthy Subjects.
Purpose To evaluate the correlation between the two methods of measuring the choroidal thickness around the optic nerve head (ONH). Methods We conducted a cross-sectional study. Sixty-two eyes of 62 healthy subjects were included. Using spectral domain optical coherence tomography, a peripapillary circle scan (diameter of 3.5 mm) and 24 radial B-scan images centered on the Bruch’s membrane opening (BMO) were obtained. Peripapillary choroidal thickness (PPCT) and juxtapapillary choroidal thickness (JPCT) were measured using circle and radial B-scan images, respectively. Correlation and agreements between values measured by two methods were analyzed. Factors associated with PPCT and JPCT, and the difference between the values measured by the two methods were evaluated. Results A total of 62 eyes of 62 healthy subjects were enrolled. Average PPCT and JPCT were 165.2 ± 50.1 and 139.7 ± 39.2 μm, respectively. The linear regression analysis showed a strong correlation between both measurements (PPCT vs. JPCT, r2 = 0.900, p < 0.001). PPCT and JPCT measurements showed good agreement in global and all six sectors (intraclass correlation coefficients >0.900). Bland-Altman plot showed good agreement between the two methods with a systematic deviation of 17.9 μm and a 95% limits of agreement (±1.96 standard deviation) of −9.6 to 60.5. In multivariate regression analysis, BMO area (β = −11.87, p = 0.002) was the only factor significantly correlated with the difference between PPCT and JPCT, which showed a negative correlation. The difference between PPCT and JPCT measurements (PPCT - JPCT) showed a divergent tendency with decreasing BMO area size. Conclusions The two measures of choroidal thickness around the ONH were well correlated. However, the peripapillary choroid was generally thicker than the juxtapapillary choroid, especially in eyes with small BMO area.
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来源期刊
Korean Journal of Ophthalmology : KJO
Korean Journal of Ophthalmology : KJO Medicine-Ophthalmology
CiteScore
2.40
自引率
0.00%
发文量
84
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