皮脂腺痣合并多发性基底细胞癌和皮外异常:遗传起源还是巧合?

IF 0.6 4区医学 Q4 DERMATOLOGY

Acta Dermatovenerologica Croatica Pub Date : 2022-11-01

Kinga Tyczyńska, Piotr K Krajewski, Iwona Chlebicka, Jacek C Szepietowski

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引用次数: 0

摘要

皮肤和皮肤外异常的关联是一种常见现象，在各种遗传综合征中被广泛描述。然而，尚未描述的综合征组合可能仍然存在。我们在此报告一位因皮脂腺痣所引起的多发性基底细胞癌而住进皮肤科的病患。除皮肤恶性肿瘤外，患者还表现为掌跖角化皮病、结节性痒疹、甲状腺功能减退、多发性腰椎异常、子宫肌瘤、卵巢囊肿和高度发育不良的结肠腺瘤。这种多种疾病的结合可能表明这些疾病的遗传起源。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Nevus Sebaceous with Multiple Basal Cell Carcinomas and Extracutaneous Abnormalities: Genetic Origin or Coincidence?

The association of cutaneous and extracutaneous abnormalities is a common phenomenon, widely described in a variety of genetic syndromes. Nevertheless, yet undescribed syndromic combinations may still exist. Herein we present a case report of a patient who was admitted to the Dermatology Department due to multiple basal cell carcinomas arising from nevus sebaceous. In addition to the cutaneous malignancies, the patient presented with palmoplantar keratoderma, prurigo nodularis, hypothyroidism, multiple lumbar abnormalities, uterine myoma, an ovarian cyst, and highly dysplastic colon adenoma. Such a combination of multiple disorders may indicate a genetic origin of the diseases.

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来源期刊

Acta Dermatovenerologica Croatica 医学-皮肤病学

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Acta Dermatovenerologica Croatica (ADC) aims to provide dermatovenerologists with up-to-date information on all aspects of the diagnosis and management of skin and venereal diseases. Accepted articles regularly include original scientific articles, short scientific communications, clinical articles, case reports, reviews, reports, news and correspondence. ADC is guided by a distinguished, international editorial board and encourages approach to continuing medical education for dermatovenerologists.