Barbara Izquierdo Coronel, Javier López Pais, Daniel Nieto Ibáñez, Renée Olsen Rodríguez, David Galán Gil, Cristina Perela Álvarez, Rocío Abad Romero, María Álvarez Bello, María Martín Muñoz, María Jesús Espinosa Pascual, Rebeca Mata Caballero, Alfonso Fraile Sanz, Paula Awamleh García, Francisco Fernández-Avilés, Joaquín J Alonso Martín
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Psychological questionnaires were completed by each patient during admission.</p><p><strong>Results: </strong>Among a total of 533 patients, 56 had MINOCA and 477 had MICAD. There were no differences in the prevalence of anxiety and insomnia between both groups: trait anxiety median value (M) MINOCA = 18 (11-34) vs. MICAD M = 19 (12-27), p = 0.8; state anxiety MINOCA M = 19 (11-29) vs. MICAD M = 19 (12.2-26), p = 0.6; and insomnia MINOCA M = 7 (3-11) vs. MICAD M = 7 (3-12), p = 0.95. More MINOCA patients had type D personality (45.0% vs. 28.5%, p = 0.03). At 3-year follow-up, there were no differences in mortality between MINOCA and MICAD (hazard ratio [HR] 0.78, 95% confidence interval [CI] 0.28-2.17) in major adverse cerebral or cardiovascular events (MACCE) (HR 0.71, 95% CI 0.38-1.31). Scores of trait anxiety and negative affectivity were significantly associated with MACCE (HR 1.65, 95% CI [1.05-2.57]; HR 1.75, 95% CI [1.11-2.77], respectively). High insomnia levels were associated with greater mortality (HR 2.72, 95% CI [1.12-6.61]).</p><p><strong>Conclusions: </strong>Anxiety and insomnia levels were similar between patients with MINOCA and those with MICAD, whilst the prevalence of type D personality was higher in the MINOCA than in the MICAD group. 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The aim of this study is to compare the prevalence of anxiety, insomnia, and type D personality between MINOCA and MICAD and their impact on prognosis.</p><p><strong>Methods: </strong>Patients with myocardial infarction undergoing coronary angiography were prospectively enrolled. Psychological questionnaires were completed by each patient during admission.</p><p><strong>Results: </strong>Among a total of 533 patients, 56 had MINOCA and 477 had MICAD. There were no differences in the prevalence of anxiety and insomnia between both groups: trait anxiety median value (M) MINOCA = 18 (11-34) vs. MICAD M = 19 (12-27), p = 0.8; state anxiety MINOCA M = 19 (11-29) vs. MICAD M = 19 (12.2-26), p = 0.6; and insomnia MINOCA M = 7 (3-11) vs. MICAD M = 7 (3-12), p = 0.95. More MINOCA patients had type D personality (45.0% vs. 28.5%, p = 0.03). 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引用次数: 0
摘要
背景：有人认为，心肌梗死和非阻塞性冠状动脉（MINOCA）患者比阻塞性冠状动脉疾病（MICAD）患者有更多的心理情感障碍。本研究旨在比较 MINOCA 和 MICAD 患者焦虑、失眠和 D 型人格的患病率及其对预后的影响：方法：对接受冠状动脉造影术的心肌梗死患者进行前瞻性登记。方法：对接受冠状动脉造影术的心肌梗死患者进行前瞻性研究，每位患者在入院时填写心理问卷：在 533 名患者中，56 人患有 MINOCA，477 人患有 MICAD。两组患者的焦虑和失眠发生率无差异：特质焦虑中值（M）MINOCA = 18 (11-34) vs. MICAD M = 19 (12-27)，P = 0.8；状态焦虑 MINOCA M = 19 (11-29) vs. MICAD M = 19 (12.2-26)，P = 0.6；失眠 MINOCA M = 7 (3-11) vs. MICAD M = 7 (3-12)，P = 0.95。更多的 MINOCA 患者具有 D 型人格（45.0% 对 28.5%，P = 0.03）。在 3 年的随访中，MINOCA 和 MICAD 的死亡率（危险比 [HR]0.78，95% 置信区间 [CI]0.28-2.17）和重大不良脑或心血管事件（MACCE）（HR 0.71，95% CI 0.38-1.31）没有差异。特质焦虑和负性情感得分与 MACCE 有显著相关性（分别为 HR 1.65，95% CI [1.05-2.57]；HR 1.75，95% CI [1.11-2.77]）。高失眠水平与更高的死亡率相关（HR 2.72，95% CI [1.12-6.61]）：结论：MINOCA和MICAD患者的焦虑和失眠程度相似，而MINOCA组的D型人格患病率高于MICAD组。特质焦虑、失眠和负性情感得分越高，随访3年后的预后越差。
Prevalence and prognosis of anxiety, insomnia, and type D personality in patients with myocardial infarction: A Spanish cohort.
Background: It has been suggested that patients with myocardial infarction and non-obstructive coronary arteries (MINOCA) have more psycho-emotional disorders than patients with obstructive coronary artery disease (MICAD). The aim of this study is to compare the prevalence of anxiety, insomnia, and type D personality between MINOCA and MICAD and their impact on prognosis.
Methods: Patients with myocardial infarction undergoing coronary angiography were prospectively enrolled. Psychological questionnaires were completed by each patient during admission.
Results: Among a total of 533 patients, 56 had MINOCA and 477 had MICAD. There were no differences in the prevalence of anxiety and insomnia between both groups: trait anxiety median value (M) MINOCA = 18 (11-34) vs. MICAD M = 19 (12-27), p = 0.8; state anxiety MINOCA M = 19 (11-29) vs. MICAD M = 19 (12.2-26), p = 0.6; and insomnia MINOCA M = 7 (3-11) vs. MICAD M = 7 (3-12), p = 0.95. More MINOCA patients had type D personality (45.0% vs. 28.5%, p = 0.03). At 3-year follow-up, there were no differences in mortality between MINOCA and MICAD (hazard ratio [HR] 0.78, 95% confidence interval [CI] 0.28-2.17) in major adverse cerebral or cardiovascular events (MACCE) (HR 0.71, 95% CI 0.38-1.31). Scores of trait anxiety and negative affectivity were significantly associated with MACCE (HR 1.65, 95% CI [1.05-2.57]; HR 1.75, 95% CI [1.11-2.77], respectively). High insomnia levels were associated with greater mortality (HR 2.72, 95% CI [1.12-6.61]).
Conclusions: Anxiety and insomnia levels were similar between patients with MINOCA and those with MICAD, whilst the prevalence of type D personality was higher in the MINOCA than in the MICAD group. Higher scores in trait anxiety, insomnia, and negative affectivity were related to a worse prognosis at 3-year follow-up.
期刊介绍：
Cardiology Journal is a scientific, peer-reviewed journal covering a broad spectrum of topics in cardiology. The journal has been published since 1994 and over the years it has become an internationally recognized journal of cardiological and medical community.
Cardiology Journal is the journal for practicing cardiologists, researchers, and young trainees benefiting from broad spectrum of useful educational content.
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