精神分裂症精神药物治疗的未来：更多的非典型抗精神病药物？猜猜看

Q3 Medicine

Psychopharmacology bulletin Pub Date : 2023-02-28

Ahmed Naguy, Saxby Pridmore, Bibi Alamiri

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引用次数: 0

摘要

没有一种单一的神经递质畸变可以解释精神分裂症综合征的异质性，因此，仅利用单一神经递质系统（如 DA 阻断）的治疗策略不太可能在临床上取得完全成功。因此，亟需开发出DA拮抗之外的新型抗精神病药物。在这方面，作者简要介绍了五种听起来很有前景的药物，它们可能会为精神分裂症的精神药物治疗带来新的火花。本文是作者上一篇关于精神分裂症精神药物疗法未来的文章的续篇。

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The Future of Schizophrenia Psychopharmacotherapy: More Antipsychotic Atypicality? Guess So!

No single neurotransmitter aberration could explain the heterogeneity of schizophrenia syndrome and thus, treatment strategies capitalizing solely on a single neurotransmitter system (e.g., DA blockade) is less likely to be fully successful on clinical grounds. Hence, there is a pressing need to develop newer antipsychotics above and beyond DA antagonism. In this regard, authors brief on five agents that sound pretty promising and might usher in a new sparkle in the psychopharmacotherapy of schizophrenia. This paper is a sequel for authors' previous article on future of schizophrenia psychopharmacotherapy.

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来源期刊

Psychopharmacology bulletin PHARMACOLOGY & PHARMACY-PSYCHIATRY

CiteScore

2.70

自引率

0.00%

发文量

期刊介绍： Information not localized