珊瑚微生物组:了解珊瑚-微生物群相互作用的分子机制。

IF 10.1 2区 生物学 Q1 MICROBIOLOGY
Amin R Mohamed, Michael A Ochsenkühn, Ahmed Kazlak, Ahmed Moustafa, Shady A Amin
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引用次数: 4

摘要

珊瑚与不同王国的不同微生物生活在一种复杂的多方共生关系中,其中一些微生物与重要功能有关,例如与抵御气候变化有关的功能。然而,知识差距和技术挑战限制了我们对珊瑚内部复杂共生关系的性质和功能意义的理解。在这里,我们概述了珊瑚微生物组的复杂性,重点是经过充分研究和神秘微生物的分类多样性和功能。对珊瑚文献的挖掘表明,虽然珊瑚共有三分之一的海洋细菌门,但已知的细菌共生体和珊瑚的拮抗剂只占这种多样性的一小部分,这些分类群聚集在选定的属中,这表明选择性进化机制使这些细菌能够在全生物中获得一个生态位。讨论了珊瑚微生物组研究的最新进展,旨在利用微生物组操作来提高珊瑚的适应性,以帮助减轻与热应激相关的死亡率。然后,通过描述已知的识别模式、潜在的微生物衍生的珊瑚表观基因组效应蛋白和珊瑚基因调控,深入了解微生物群与宿主交流和改变宿主反应的潜在机制。最后,强调了用于研究珊瑚的组学工具的力量,重点是一个综合的宿主微生物群多组学框架,以了解共生和气候变化驱动的微生态失调的潜在机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The coral microbiome: towards an understanding of the molecular mechanisms of coral-microbiota interactions.

The coral microbiome: towards an understanding of the molecular mechanisms of coral-microbiota interactions.

The coral microbiome: towards an understanding of the molecular mechanisms of coral-microbiota interactions.

The coral microbiome: towards an understanding of the molecular mechanisms of coral-microbiota interactions.

Corals live in a complex, multipartite symbiosis with diverse microbes across kingdoms, some of which are implicated in vital functions, such as those related to resilience against climate change. However, knowledge gaps and technical challenges limit our understanding of the nature and functional significance of complex symbiotic relationships within corals. Here, we provide an overview of the complexity of the coral microbiome focusing on taxonomic diversity and functions of well-studied and cryptic microbes. Mining the coral literature indicate that while corals collectively harbour a third of all marine bacterial phyla, known bacterial symbionts and antagonists of corals represent a minute fraction of this diversity and that these taxa cluster into select genera, suggesting selective evolutionary mechanisms enabled these bacteria to gain a niche within the holobiont. Recent advances in coral microbiome research aimed at leveraging microbiome manipulation to increase coral's fitness to help mitigate heat stress-related mortality are discussed. Then, insights into the potential mechanisms through which microbiota can communicate with and modify host responses are examined by describing known recognition patterns, potential microbially derived coral epigenome effector proteins and coral gene regulation. Finally, the power of omics tools used to study corals are highlighted with emphasis on an integrated host-microbiota multiomics framework to understand the underlying mechanisms during symbiosis and climate change-driven dysbiosis.

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来源期刊
FEMS microbiology reviews
FEMS microbiology reviews 生物-微生物学
CiteScore
17.50
自引率
0.90%
发文量
45
审稿时长
6-12 weeks
期刊介绍: Title: FEMS Microbiology Reviews Journal Focus: Publishes reviews covering all aspects of microbiology not recently surveyed Reviews topics of current interest Provides comprehensive, critical, and authoritative coverage Offers new perspectives and critical, detailed discussions of significant trends May contain speculative and selective elements Aimed at both specialists and general readers Reviews should be framed within the context of general microbiology and biology Submission Criteria: Manuscripts should not be unevaluated compilations of literature Lectures delivered at symposia must review the related field to be acceptable
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