低级别头颈部多形真皮肉瘤与高级别头颈部多形真皮肉瘤的生存差异及头皮病例回顾。

Q2 Medicine
World Journal of OtorhinolaryngologyHead and Neck Surgery Pub Date : 2022-04-18 eCollection Date: 2023-03-01 DOI:10.1002/wjo2.64
Tyler A Janz, Barry D Long, Rohan R Joshi, Orly M Coblens
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引用次数: 0

摘要

目的:研究头颈部多形性真皮肉瘤(PDS)按肿瘤等级划分的生存率,并回顾一例头皮PDS病例:研究头颈部(H&N)多形性真皮肉瘤(PDS)按肿瘤等级划分的生存率,并回顾一例头皮PDS病例:方法:根据H&N PDS的诊断结果,纳入了1980年至2016年监测、流行病学和最终结果(SEER)数据库中的患者。采用卡普兰-梅耶尔分析法进行生存期估计。此外,还介绍了一例III级H&N PDS病例:结果:共发现 277 例 PDS 病例。诊断时的平均年龄为 75.1 岁(SD:13.5)。234例(86.7%)患者为男性。87%的患者接受了手术治疗。I、II、III和IV级PDS的5年总生存率分别为69%、60%、50%和42%(P = 0.03):结论:H&N PDS 最常见于老年男性。结论:H&N PDS 最常发生在老年男性身上,手术治疗是 H&N PDS 治疗中经常使用的方法。肿瘤分级越高,生存率越低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Survival differences of low-grade versus high-grade head and neck pleomorphic dermal sarcomas and a review of a scalp case.

Survival differences of low-grade versus high-grade head and neck pleomorphic dermal sarcomas and a review of a scalp case.

Survival differences of low-grade versus high-grade head and neck pleomorphic dermal sarcomas and a review of a scalp case.

Objective: To examine survival by tumor grade of pleomorphic dermal sarcomas (PDS) of the head and neck (H&N) and review a scalp PDS case.

Methods: Patients in the Surveillance, Epidemiology, and End Results (SEER) database were included from 1980 to 2016 based on a diagnosis of H&N PDS. Survival estimates were performed using Kaplan-Meier analysis. Additionally, a case of a grade III H&N PDS is presented.

Results: Two hundred-seventy cases of PDS were identified. The mean age at diagnosis was 75.1 years (SD: 13.5). Two hundred-thirty-four (86.7%) patients were male. Eighty-seven percent of patients received surgery as a part of their care. The 5-year overall survival rates for grades I, II, III, and IV PDSs were 69%, 60%, 50%, and 42%, respectively (P = 0.03).

Conclusions: H&N PDS occurs most commonly in older-age males. Surgical management is frequently a part of H&N PDS care. Survival rates significantly decline based on tumor grade.

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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
283
审稿时长
13 weeks
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