肉毒杆菌抗毒素治疗医源性肉毒中毒1例。

IF 0.8 4区医学 Q4 CLINICAL NEUROLOGY

Clinical Neuropharmacology Pub Date : 2023-03-01 DOI:10.1097/WNF.0000000000000535

Ozge Gonul Oner, Hasan Can Gudek, Ozdem Erturk Cetin, Serkan Demir

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引用次数: 1

摘要

目的:A型肉毒毒素广泛用于治疗痉挛、局局性肌张力障碍、面肌痉挛、多汗症、斜视、慢性偏头痛以及美容目的。治疗使用通常是有效和安全的。然而，如果毒素进入血管间隙并通过周围胆碱能神经末梢，则可能导致医源性肉毒中毒。方法:我们报告了一位被诊断为医源性肉毒杆菌中毒的患者，并在暴露后第15天给予抗毒素治疗。结果:抗毒素给药后，疗效显著。结论:在本报告中，我们想要评估一个新的医源性肉毒杆菌中毒病例，并强调抗毒素给药的重要性，而不考虑接触时间对进行性瘫痪患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Iatrogenic Botulism: A Case Treated With Botulinum Antitoxin.

Objective: Botulinum toxin type A is widely used for the treatment of spasticity, focal dystonia, hemifacial spasm, hyperhidrosis, strabismus, chronic migraine, and also cosmetic purposes. Therapeutic use is commonly effective and safe. However, if toxin enters the vascular space and gets through to peripheral cholinergic nerve terminals, it may lead to iatrogenic botulism.

Method: We presented a patient who is diagnosed as iatrogenic botulism and treated with antitoxin at the 15th day of the exposure.

Results: After the antitoxin administration, dramatical response to the treatment was observed.

Conclusions: In this report, we want to evaluate a new case of iatrogenic botulism and emphasize the importance of antitoxin administration regardless the timing of the exposure for patients with progressing paralysis.

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来源期刊

Clinical Neuropharmacology 医学-临床神经学

CiteScore

1.20

自引率

10.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Clinical Neuropharmacology is a peer-reviewed journal devoted to the pharmacology of the nervous system in its broadest sense. Coverage ranges from such basic aspects as mechanisms of action, structure-activity relationships, and drug metabolism and pharmacokinetics, to practical clinical problems such as drug interactions, drug toxicity, and therapy for specific syndromes and symptoms. The journal publishes original articles and brief reports, invited and submitted reviews, and letters to the editor. A regular feature is the Patient Management Series: in-depth case presentations with clinical questions and answers.