手术患者术前青霉素过敏试验的实施。

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A&A Practice Pub Date : 2023-02-03 eCollection Date: 2023-02-01 DOI:10.1213/XAA.0000000000001659

Ravindra Alok Gupta, Howard Lee, Obianuju Okocha

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引用次数: 0

摘要

青霉素过敏是报道最多的免疫球蛋白E (IgE)介导的反应。大约10%的普通人群和20%的住院患者有青霉素过敏史。未经证实的青霉素过敏和随后使用二线抗生素与发病率增加有关。然而，当进行青霉素过敏试验时，ige介导的反应发生率极低;事实上，青霉素过敏试验的阴性预测值超过99%。本文旨在简要介绍在手术患者术前评估中如何将安全的青霉素过敏试验作为常规试验。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Implementing Preoperative Penicillin Allergy Testing in Surgical Patients.

Penicillin allergy is the most reported immunoglobulin E (IgE)-mediated reaction. About 10% of the general population and 20% of hospitalized patients have a history of penicillin allergy. Unconfirmed penicillin allergy with subsequent administration of second-line antibiotics has been associated with increased morbidity. However, when penicillin allergy testing is performed, the incidence of IgE-mediated reactions is extremely low; in fact, the negative predictive value of penicillin allergy testing exceeds 99%. This article aims to briefly describe implementing safe penicillin allergy testing as a routine test during the preoperative evaluation of surgical patients.

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来源期刊

A&A Practice ANESTHESIOLOGY-

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期刊介绍： A & A Case Reports, our new online journal publishing Case Reports, related Editorial Commentary, and Correspondence. Anesthesia & Analgesia 1 and Anesthesiology 2 recently announced that they were suspending publication of Case Reports. One reason is that Case Reports typically reduce the Impact Factor of a journal because they are rarely cited. Regardless of the merits of Impact Factor as a metric of journal worth, journals and their editors necessarily consider Impact Factor in strategic planning. At the same time, Case Reports are appreciated by readers for describing “real life” management of difficult or unusual cases not often encountered by practitioners. In a recent issue of Anesthesia & Analgesia, Steven Shafer1 identified many Case Reports whose publication launched productive careers dedicated to solving the puzzle posed by an unusual observation in a single patient.