{"title":"基因组编辑的短暂而独特的历史","authors":"Dana Carroll","doi":"10.1016/j.ggedit.2021.100002","DOIUrl":null,"url":null,"abstract":"<div><p>This article reviews some of the early events leading to the development of the first genome editing platform, zinc-finger nucleases. It describes some of the earliest uses of ZFNs and the advent of the more user-friendly platforms, TALENs and CRISPR. Some current applications and their implications are reviewed, followed by a brief look into the future.</p></div>","PeriodicalId":73137,"journal":{"name":"Gene and genome editing","volume":"1 ","pages":"Article 100002"},"PeriodicalIF":0.0000,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ggedit.2021.100002","citationCount":"4","resultStr":"{\"title\":\"A short, idiosyncratic history of genome editing\",\"authors\":\"Dana Carroll\",\"doi\":\"10.1016/j.ggedit.2021.100002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>This article reviews some of the early events leading to the development of the first genome editing platform, zinc-finger nucleases. It describes some of the earliest uses of ZFNs and the advent of the more user-friendly platforms, TALENs and CRISPR. Some current applications and their implications are reviewed, followed by a brief look into the future.</p></div>\",\"PeriodicalId\":73137,\"journal\":{\"name\":\"Gene and genome editing\",\"volume\":\"1 \",\"pages\":\"Article 100002\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.ggedit.2021.100002\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gene and genome editing\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666388021000022\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gene and genome editing","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666388021000022","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
This article reviews some of the early events leading to the development of the first genome editing platform, zinc-finger nucleases. It describes some of the earliest uses of ZFNs and the advent of the more user-friendly platforms, TALENs and CRISPR. Some current applications and their implications are reviewed, followed by a brief look into the future.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
