用于心肌炎症分子成像的新型放射性示踪剂:非18f - fdg放射性示踪剂临床转化的最新进展

IF 0.6 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Current Cardiovascular Imaging Reports Pub Date : 2023-01-01 DOI:10.1007/s12410-023-09574-4

Tiantian Shi, Edward J Miller

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引用次数: 0

摘要

综述目的:本文的目的是提供非18f - fdg放射性示踪剂在心肌炎症性疾病中的最新进展，重点是心肌结节病和心肌炎。最新发现:针对炎症分子特征的新型放射性示踪剂有可能揭示炎性心肌病(如结节病和心肌炎)发病机制的关键分子机制。这些放射性示踪剂可能提供独特的机会，以改善机制的洞察力，更高的特异性，更好地量化疾病活动，以及潜在的指导和监测免疫调节疗法。摘要:新型放射性示踪剂为心脏结节病和心肌炎的诊断、预后表现和治疗指导提供了独特的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Novel Radiotracers for Molecular Imaging of Myocardial Inflammation: an Update Focused on Clinical Translation of Non-18F-FDG Radiotracers.

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Novel Radiotracers for Molecular Imaging of Myocardial Inflammation: an Update Focused on Clinical Translation of Non-18F-FDG Radiotracers.

Purpose of review: The purpose of this paper is to provide a focused update on recent advances in non-18F-FDG radiotracers for myocardial inflammatory diseases, with a focus on cardiac sarcoidosis and myocarditis.

Recent findings: Novel radiotracers targeting molecular features of inflammation have the potential to visualize underlying molecular mechanisms key to the pathogenesis of inflammatory cardiomyopathies such as sarcoidosis and myocarditis. These radiotracers may provide unique opportunities for improved mechanistic insight, higher specificity, and better quantification of disease activity, as well as potential for guidance and monitoring of immunomodulatory therapies.

Summary: Novel radiotracers provide unique possibilities in diagnosis, prognostic performance, and therapy guidance for cardiac sarcoidosis and myocarditis.

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来源期刊

Current Cardiovascular Imaging Reports RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

2.20

自引率

0.00%

发文量

期刊介绍： Cardiovascular imaging technologies now play an expanded role in clinical practice. Beyond the diagnosis of a disease process, these techniques are rapidly transitioning to help guide therapy. The journal aims to keep readers current with rapidly evolving advances in instrumentation and imaging procedures that support the expanded role of these technologies in clinical practice. The journal intends to place the entire area of cardiovascular imaging in its proper prospective by establishing the indications and limitations of each imaging technique and by summarizing recent clinical advances. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field, including cardiac magnetic resonance, nuclear imaging, echocardiography, cardiac computed tomography, intravascular, molecular, and hybrid imaging. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An Editorial Board of internationally diverse members ensures that topics include emerging research and suggests topics of special interest to their country/region. We also provide commentaries from well-known figures in the field.