过去15年来埃塞俄比亚用于肝炎管理的药用植物:系统综述。

IF 2.6 Q2 GASTROENTEROLOGY & HEPATOLOGY
Yibeltal Aschale, Bantayehu Addis Tegegne, Wubetu Yihunie
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引用次数: 0

摘要

背景:在埃塞俄比亚,利用植物资源治疗人类和动物疾病得到了极大的关注。植物中的化合物含有丰富的生物活性成分,能够治疗许多并发症。该综述旨在提供埃塞俄比亚过去15年来用于治疗肝炎的植物的最新清单。方法:在2022年9月1日至10月15日期间,使用标准检索词对电子数据库(PubMed、Google Scholar、Science Direct和Scopus)进行系统、全面的检索。2007年1月1日至2021年12月31日期间在埃塞俄比亚进行的以英文撰写和发表的原始研究报告将肝炎作为一种由药用植物治疗的疾病纳入了审查。埃塞俄比亚和厄立特里亚花卉之外的植物被排除在外。数据在Microsoft Excel中从原始论文的文本和表格中提取。质量通过应用乔安娜布里格斯研究所关键评估清单进行评估。结果:在数据库中检索到论文317篇。在剔除重复和筛选后,15篇文章符合纳入标准,入选最终评审。在鉴定的24种植物中,35.7%为草本植物。叶和根是制备药物的主要植物部位,各占35.7%。叶和根的综合利用占10.7%。夹竹桃科、菊科、大戟科、葫芦科和豆科是数量最多的植物物种。89.3%的药物是口服的。结论:植物以草本植物为主,常用植物部位为叶和根。从本综述中获得的证据表明,许多植物已被用于治疗肝炎。此外,研究结果可为研制抗肝炎新药提供初步信息。因此,学者们需要适当地认识、记录和保存植物及其相关知识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review.

Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review.

Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review.

Medicinal Plants Used for the Management of Hepatitis Over the Past 15 Years in Ethiopia: A Systematic Review.

Background: Treatment of human and animal ailments using botanical sources has obtained significant attention in Ethiopia. The compounds available in plants comprise a plentiful source of bioactive ingredients able to treat many complications. The review aimed to present an updated list of plants used for managing hepatitis over the past 15 years in Ethiopia.

Methods: Systematic, comprehensive search was undertaken from electronic databases (PubMed, Google Scholar, Science Direct, and Scopus) between September 01 and October 15, 2022, using standard search terms. Original researches carried out in Ethiopia, written and published in English between January 01/2007 and December 31/2021, and reported hepatitis as a disease treated by medicinal plants were included in the review. Plants beyond the list of Ethiopian and Eritrean floral were excluded. Data were extracted from texts and tables of original papers on a Microsoft Excel. Quality was assessed by applying the Joanna Briggs Institute Critical Appraisal Checklist.

Results: A total of 317 papers were obtained from the database search. After removing duplicates and screening, 15 articles fit the inclusion criteria and selected for final review. Of the 24 plants identified, 35.7% were herbs. Leaf and root (35.7% each) were the predominant plant parts used for remedy preparation. Combined use of leaf and root comprised 10.7%. The families Apocynaceae, Asteraceae, Euphorbiaceae, Cucurbitaceae, and Fabaceae comprise the highest number of plant species. About 89.3% of remedies were administered orally.

Conclusion: The majority of plants belong to herbs and the frequently used plant parts are leaf and roots. Evidence generated from the present review indicated that lots of plants have been used to manage hepatitis. Moreover, the findings could serve as preliminary information to formulate new drugs acting against hepatitis. Therefore, it is desirable for scholars to recognize, document, and keep plants and the associated knowledge appropriately.

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来源期刊
Hepatic Medicine : Evidence and Research
Hepatic Medicine : Evidence and Research GASTROENTEROLOGY & HEPATOLOGY-
自引率
0.00%
发文量
15
审稿时长
16 weeks
期刊介绍: Hepatic Medicine: Evidence and Research is an international, peer-reviewed, open access, online journal. Publishing original research, reports, editorials, reviews and commentaries on all aspects of adult and pediatric hepatology in the clinic and laboratory including the following topics: Pathology, pathophysiology of hepatic disease Investigation and treatment of hepatic disease Pharmacology of drugs used for the treatment of hepatic disease Although the main focus of the journal is to publish research and clinical results in humans; preclinical, animal and in vitro studies will be published where they will shed light on disease processes and potential new therapies. Issues of patient safety and quality of care will also be considered. As of 1st April 2019, Hepatic Medicine: Evidence and Research will no longer consider meta-analyses for publication.
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