传统方剂治疗季节性感染的镇痛解热作用评价

K. Parthiban, S. Natesan, G. Sekar, Krishnamoorthi Mahalakshm
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引用次数: 1

摘要

对于生活在发展中国家农村地区的数百万人来说,传统疗法和药物是主要的,有时是唯一的保健来源。本研究的目的是研究三种不同剂量的单株植物提取物和多药复方(PHF)对白化大鼠的镇痛解热作用。植物材料在沸水蒸馏水中提取6小时,过滤、浓缩、干燥。以水、甘油混合物和2%金合欢为原料,以不同的提取物剂量配制成多草药液体剂型。上述制剂口服1ml用于研究。以戊唑辛和扑热息痛分别为标准药物。单株提取液悬浮于2%金合欢溶液中进行实验。phf1和phf2的镇痛、解热活性有显著性差异(P<0.01和P<0.05), PHF3无显著性差异。在单个植物提取物中,活性略显著(P<0.05)。DOI: http://dx.doi.org/10.3329/icpj.v2i9.16075国际现代医药杂志,2013年8月,2(9):143-147
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of analgesic and antipyretic activity of traditional formula used in the treatment of seasonal infections
Traditional treatments and medicines are the main sometimes the only source of health care for millions of people living in rural areas of developing countries. The aim of the present study is to investigate the analgesic and antipyretic activity of individual plant extracts and poly-herbal formula [PHF] made in to liquid dosage form of three different doses in albino rats. The plant materials were extracted in boiling distilled water for six hours, filtered, concentrated and dried. The aqueous extracts were prepared in to poly-herbal liquid dosage form by using water, glycerol mixture and acacia 2% in three different preparation of varying extract doses.1ml of above preparations orally fed for investigation. Pentozocine and paracetamol was used as standard drugs respectively. For individual plants the extracts were suspended in 2% acacia solution and performed. The results of analgesic and anti-pyretic activity of PHF 1 and PHF 2 showed significant results (P<0.01 and P<0.05 respectively) and PHF3 did not show any significant results. In the individual plant extracts slightly significant activity (P<0.05) was observed. DOI:  http://dx.doi.org/10.3329/icpj.v2i9.16075 International Current Pharmaceutical Journal, August 2013, 2(9): 143-147
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