Perampanel过量致呼吸衰竭1例。

Yangmi Park, Seondeuk Kim, Dae Lim Koo, Hyunwoo Nam
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引用次数: 0

摘要

Perampanel是一种新型抗癫痫药物,已被用作局灶性癫痫发作的辅助治疗。到目前为止,还没有报告表明perampanel对成人有呼吸抑制的副作用。在此,我们报告了一名51岁的局灶性癫痫患者,在意外服用66 mg perampanel后出现2型呼吸衰竭。当需要给患者使用高剂量perampanel时,临床医生应考虑呼吸损伤的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Case of Perampanel Overdose Presenting with Respiratory Failure.

A Case of Perampanel Overdose Presenting with Respiratory Failure.

Perampanel is a novel antiepileptic drug that has been used as an adjunctive treatment for focal-onset seizures. No reports to date have documented respiratory suppression as a side effect of perampanel in adults. Herein, we report a 51-year-old man with focal epilepsy presented with type 2 respiratory failure after accidently consuming of 66 mg of perampanel. Clinicians should consider the possibility of respiratory compromise whenever a high dose of perampanel needs to be administered to patients.

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