脑内皮细胞产生前列腺素E2与发热的发生。

IF 2.6 4区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

DNA and cell biology Pub Date : 2023-03-01 DOI:10.1089/dna.2022.0662

Anders Blomqvist

引用次数: 1

摘要

我们最近证明，前列腺素在脑内皮细胞的生产是必要的和充分的发热产生在全身免疫挑战。我在此根据先前的文献讨论这一发现，并指出一些尚未解决的问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Prostaglandin E<sub>2</sub> Production by Brain Endothelial Cells and the Generation of Fever.

查看原文本刊更多论文

Prostaglandin E₂ Production by Brain Endothelial Cells and the Generation of Fever.

We recently demonstrated that prostaglandin production in brain endothelial cells is both necessary and sufficient for the generation of fever during systemic immune challenge. I here discuss this finding in light of the previous literature and point to some unresolved issues.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

DNA and cell biology 生物-生化与分子生物学

CiteScore

6.60

自引率

0.00%

发文量

审稿时长

1.5 months

期刊介绍： DNA and Cell Biology delivers authoritative, peer-reviewed research on all aspects of molecular and cellular biology, with a unique focus on combining mechanistic and clinical studies to drive the field forward. DNA and Cell Biology coverage includes: Gene Structure, Function, and Regulation Gene regulation Molecular mechanisms of cell activation Mechanisms of transcriptional, translational, or epigenetic control of gene expression Molecular Medicine Molecular pathogenesis Genetic approaches to cancer and autoimmune diseases Translational studies in cell and molecular biology Cellular Organelles Autophagy Apoptosis P bodies Peroxisosomes Protein Biosynthesis and Degradation Regulation of protein synthesis Post-translational modifications Control of degradation Cell-Autonomous Inflammation and Host Cell Response to Infection Responses to cytokines and other physiological mediators Evasive pathways of pathogens.