埃塞俄比亚南部希达马阿瓦萨市阿瓦萨大学综合专科医院艾滋病患者治疗性喂养计划的营养治疗结果及其预测因素:一项回顾性队列研究。

IF 1.5 Q4 INFECTIOUS DISEASES

HIV AIDS-Research and Palliative Care Pub Date : 2023-01-01 DOI:10.2147/HIV.S395936

Helen Tadesse, Alemayehu Toma

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引用次数: 1

摘要

背景:艾滋病毒引起的营养不良在世界不同地区非常普遍，特别是在撒哈拉以南非洲。食品干预一揽子计划是通过营养评估、咨询和护理来解决艾滋病毒感染者营养不良问题的战略之一。然而，对这些患者在治疗方案中的干预结果知之甚少。因此，本研究旨在评估埃塞俄比亚成年艾滋病毒阳性营养不良个体的营养治疗结果及其预测因素。方法:对阿瓦萨大学综合专科医院成人抗逆转录病毒治疗门诊进行回顾性队列研究。采用结构化问卷法，通过处方登记簿和患者卡片提取419例患者的数据。采用Cox-proportional Hazard模型通过确定风险比和95%置信区间来评估统计学显著性。结果:成人HIV患者经处方治疗入组后营养不良恢复的比例为53.0%。在最终模型中，发现与处方食品营养治疗效果良好相关的变量是女性(调整风险比(AHR) = 3.38, 95% CI: 2.15, 5.32)，中等教育(AHR = 2.16, 95% CI: 1.11, 4.18)，高等教育(AHR = 3.75, 95% CI: 1.66, 8.48)， SAM (AHR = 0.20;95% CI: 0.12, 0.35)和HAART (AHR = 2.70, 95% CI: 1.50, 4.86)。基线营养评估时患有严重急性营养不良(SAM) (AHR = 3.42, 95% CI;2.81, 5.15)，接受抗逆转录病毒治疗超过12个月(AHR = 0.26, 95% CI: 0.13, 0.84)和检测呈阳性后立即开始HAART治疗(AHR = 0.26, 95% CI: 0.13, 0.84)与营养治疗失败显著相关。结论:经处方治疗后，53%的艾滋病患者营养不良恢复。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Nutritional Treatment Outcomes of Therapeutic Feeding Program and Its Predictors Among HIV Patients at Hawassa University Comprehensive Specialized Hospital, Hawassa City, Sidama, Southern Ethiopia: A Retrospective Cohort Study.

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Background: HIV-induced malnutrition is highly prevalent in different parts of the world particularly in sub-Saharan Africa. The food intervention package is one of the strategies that targets malnutrition among HIV-infected people through nutritional evaluation, counseling and care. However, little is known concerning the outcomes of intervention in such patients in treatment program. Therefore, this study aimed to assess nutritional treatment outcomes and its predictors among adult HIV-positive undernourished individuals in Ethiopia.

Methods: Facility based retrospective cohort study was deployed in Adult Antiretroviral therapy clinic of Hawassa University Comprehensive Specialized Hospital. Data of 419 patients were extracted from the food by prescription registration book and patient cards using structured questionnaires. Statistical significance was assessed using Cox-proportional Hazard model by determining hazard ratios and 95% confidence interval.

Results: The proportion of adult HIV patients who recovered from malnutrition after they were enrolled in the food by prescription therapy was 53.0%. The variables found to have an association with good nutritional treatment outcomes of food by prescription in the final model are being female (Adjusted Hazard Ratio (AHR) = 3.38, 95% CI: 2.15, 5.32), secondary education (AHR = 2.16, 95% CI: 1.11, 4.18), tertiary education (AHR = 3.75, 95% CI: 1.66, 8.48), SAM (AHR = 0.20; 95% CI: 0.12, 0.35), and HAART (AHR = 2.70, 95% CI: 1.50, 4.86). Having Severe Acute Malnutrition (SAM) at baseline nutritional assessment (AHR = 3.42, 95% CI; 2.81, 5.15), taking ART for more than 12 months (AHR = 0.26, 95% CI: 0.13, 0.84) and starting HAART immediately after testing positive (AHR = 0.26, 95% CI: 0.13, 0.84) are significantly associated with nutritional treatment failure.

Conclusion: Fifty-three percent of HIV patients recovered from malnutrition after they were enrolled in the food by prescription therapy.

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来源期刊

HIV AIDS-Research and Palliative Care INFECTIOUS DISEASES-

CiteScore

3.00

自引率

6.70%

发文量

审稿时长

16 weeks

期刊介绍： About Dove Medical Press Dove Medical Press Ltd is part of Taylor & Francis Group, the Academic Publishing Division of Informa PLC. We specialize in the publication of Open Access peer-reviewed journals across the broad spectrum of science, technology and especially medicine. Dove Medical Press was founded in 2003 with the objective of combining the highest editorial standards with the ''best of breed'' new publishing technologies. We have offices in Manchester and London in the United Kingdom, representatives in Princeton, New Jersey in the United States, and our editorial offices are in Auckland, New Zealand. Dr Scott Fraser is our Medical Director based in the UK. He has been in full time clinical practice for over 20 years as well as having an active research interest.