tl18131 -创伤后骨关节炎患者距下关节透明质酸浸润的功能评价

Fernanda Ferreira Gomes, Henrique Mansur, Maria Laura Silva Gomes, D. Ramalho, Isnar Moreira de Castro Júnior
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引用次数: 0

摘要

目的:评价关节内补充粘剂治疗跟骨骨折后症状性距下骨关节炎的疗效。方法:38例平均年龄50岁的患者分为单独使用透明质酸组、单独使用皮质激素组和透明质酸与皮质激素联合使用组。每隔一周给药三次。采用美国骨科足踝学会(AOFAS)评分和视觉模拟评分(VAS)在4个不同时间点(浸润前、浸润后4周、12周和24周)评估患者的疼痛和后足功能。结果:AOFAS评分有显著改善(从基线时的中位数55和73提高到24周后的99和100;p<0.001)和VAS评分(从浸润前的中位数8和7到浸润后24周的中位数1和2;P <0.001),分别与单独使用透明质酸组和与皮质激素联合使用组比较。在第2组,仅在4周后评分就有所提高(从83到91.5和从7到5),在随访结束时恢复到接近基线值(从83到82.5和从7到7)。结论:透明质酸浸润是有效和安全的,应纳入有症状的创伤后距下骨关节炎的保守治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
TL 18131 - Functional evaluation of hyaluronic acid infiltration in the subtalar joint of patients with posttraumatic osteoarthritis
Objective: To assess the efficacy of intra-articular viscosupplementation in patients with symptomatic subtalar osteoarthritis after calcaneal fracture. Methods: Thirty-eight patients with a mean age of 50 years were divided into 3 groups: hyaluronic acid (HA) alone, corticoids alone or hyaluronic acid and corticoids combined. Three consecutive doses of the appropriate medication were administered at one-week intervals. The patients were evaluated for pain and hindfoot function using the American Orthopedic Foot and Ankle Society (AOFAS) scale and the visual analog scale (VAS) at 4 different timepoints (before infiltration and 4, 12 and 24 weeks after infiltration). Results: There was significant improvement in the AOFAS score (from medians of 55 and 73 at baseline to 99 and 100 after 24 weeks; p<0.001) and the VAS score (from medians of 8 and 7 before infiltration to 1 and 2 at 24 weeks after infiltration; p<0.001) scores in the groups with hyaluronic acid alone and in combination with corticoid, respectively. In group 2, the scores improved after only 4 weeks (from 83 to 91.5 and from 7 to 5), returning to near-baseline values at the end of the follow-up (from 83 to 82.5 and from 7 to 7). Conclusion: Infiltration with hyaluronic acid was effective and safe and should be included in the therapeutic arsenal of conservative treatments for symptomatic posttraumatic subtalar osteoarthritis.
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