检查美国儿科学会(AAP)推荐剂量维生素D对健康母乳喂养新生儿的疗效

Sajid Ali, D. I. Khan, Swaleha Akhtar, Musab Siddiqui
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引用次数: 0

摘要

摘要:背景:维生素D补充剂对于母乳喂养的新生儿是必要的,尽管对于AAP推荐的每天400 IU的维生素D剂量的有效性知之甚少。本随机对照试验评价上述剂量的疗效。方法:将28例纯母乳喂养的新生儿随机分为补充维生素D (VitD-S)组和不补充维生素D (VitD-U)组,给予维生素D- s组400IU/ D。在入组时和3个月时评估血清维生素D。结果:两组维生素D水平比较,出生时Vit D- s为20.4±8.7ng/ml, 3个月时Vit D- s为24.8±6.1ng/ml,而Vit D- u由21.4±7.8ng/ml降至14.0±5.1ng/ml,差异有统计学意义(p<0.001)。结论:维生素D缺乏症在该地区的母亲和婴儿中相当普遍,每天补充400 IU维生素D可增加血浆中25(OH)D水平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
To Check the Efficacy of American Academy of Paediatrics (AAP) Recommended Dose of Vitamin D in Healthy Breastfed Newborns
ABSTRACT: Background: Vitamin D supplements are necessary for breastfed newborns, although little is known regarding the effectiveness of AAP’s recommended dose of 400 IU per day of it. This randomized controlled trial evaluates the efficacy of above-mentioned dose. Method: Exclusively breastfed newborns (N=28) were block randomized in two groups, vitamin D supplemented (VitD-S) and without supplement (VitD-U), 400IU/day of vitamin D is provided to Vit D-S. Serum vitamin D was assessed at the enrolment and at 3 months. Results: Vitamin D level compared between two groups, in Vit D-S at birth it was 20.4±8.7ng/ml and at 3 months it rises to 24.8±6.1ng/ml while in Vit D-U fall in level is seen from 21.4±7.8ng/ml to 14.0±5.1ng/ml which is statistically significant (p<0.001). Conclusion: Vitamin D is deficiency is quite common among mothers and babies in this location, and supplementing with 400 IU of vitamin D per day increased 25(OH)D levels in the plasma.
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