{"title":"结节病:一种独特的病理生理和临床实体","authors":"Swati H. Shah","doi":"10.15713/ins.bhj.74","DOIUrl":null,"url":null,"abstract":"Abstract \nIn recent years, antibodies directed against the proteins located at the node of Ranvier have been identified in patients with immune mediated neuropathies. In this article, we review the structure of node of Ranvier and pathology associated with these antibody mediated neuropathies. We summarize the emerging concept of nodopathy/ paranodopathy, its clinical relevance and treatment implications.","PeriodicalId":85654,"journal":{"name":"The Bombay Hospital journal","volume":"22 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nodopathies: A distinct pathophysiological and clinical entity\",\"authors\":\"Swati H. Shah\",\"doi\":\"10.15713/ins.bhj.74\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract \\nIn recent years, antibodies directed against the proteins located at the node of Ranvier have been identified in patients with immune mediated neuropathies. In this article, we review the structure of node of Ranvier and pathology associated with these antibody mediated neuropathies. We summarize the emerging concept of nodopathy/ paranodopathy, its clinical relevance and treatment implications.\",\"PeriodicalId\":85654,\"journal\":{\"name\":\"The Bombay Hospital journal\",\"volume\":\"22 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-02-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Bombay Hospital journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15713/ins.bhj.74\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Bombay Hospital journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15713/ins.bhj.74","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nodopathies: A distinct pathophysiological and clinical entity
Abstract
In recent years, antibodies directed against the proteins located at the node of Ranvier have been identified in patients with immune mediated neuropathies. In this article, we review the structure of node of Ranvier and pathology associated with these antibody mediated neuropathies. We summarize the emerging concept of nodopathy/ paranodopathy, its clinical relevance and treatment implications.