具体的物质遭遇和生物医学未来的模糊承诺:生物衍生药物的案例

IF 1.3 4区 医学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Mianna Meskus, Venla Oikkonen
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引用次数: 2

摘要

使用细胞、微生物或组织等生物来源材料的治疗和预防措施往往被描述为增进未来健康的关键。本文探讨了这种愿景的物质前提条件。在女权主义新唯物主义方法的基础上,它探索了被植入生命体的生物制剂与身体充满活力的物质性之间的具体物质相遇。我们通过两种生物制剂,大流行性流感疫苗和干细胞疗法研究了具体的物质接触,重点研究了2009年大流行性流感期间疫苗相关的发作性睡病,以及针对AMD眼病的实验性干细胞疗法的不良反应。我们提出,具体化的物质遭遇的概念为STS提供了一个重要的工具,通过使风险和承诺的构成情境和治疗利用生物过程的未来的多样性可见。我们认为,生物医学未来的伦理责任愿景需要建立在对这些具体过程的细致理解之上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Embodied material encounters and the ambiguous promise of biomedical futures: The case of biologically derived medicines
Therapies and prophylactics using biologically derived materials such as cells, microbes or tissues are often portrayed as key to increased future health. This article investigates the material preconditions of such visions. Building on feminist new materialist approaches, it explores the embodied material encounters between biologicals administered into living bodies and the vibrant materiality of the body. We investigate embodied material encounters through two biologicals, pandemic vaccines and stem cell therapies, focusing on vaccine-associated narcolepsy during the 2009 pandemic, and adverse reactions in an experimental stem cell therapy targeting an eye disease called AMD. We propose that the concept of embodied material encounter provides an important tool for STS by making visible the constitutive situatedness of risk and promise and the multiplicity of futures in therapeutically harnessed biological processes. We argue that ethically accountable visions of biomedical futures need to be anchored in a nuanced understanding of these embodied processes.
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来源期刊
New Genetics and Society
New Genetics and Society 生物-生物工程与应用微生物
CiteScore
4.30
自引率
16.70%
发文量
19
审稿时长
>12 weeks
期刊介绍: New Genetics and Society: Critical Studies of Contemporary Biosciences is a world-leading journal which: -Provides a focus for interdisciplinary and multi-disciplinary, leading-edge social science research on the new genetics and related biosciences; -Publishes theoretical and empirical contributions reflecting its multi-faceted development; -Provides an international platform for critical reflection and debate; -Is an invaluable research resource for the many related professions, including health, medicine and the law, wishing to keep abreast of fast changing developments in contemporary biosciences. New Genetics and Society publishes papers on the social aspects of the new genetics (widely defined), including gene editing, genomics, proteomics, epigenetics and systems biology; and the rapidly developing biosciences such as biomedical and reproductive therapies and technologies, xenotransplantation, stem cell research and neuroscience. Our focus is on developing a better understanding of the social, legal, ethical and policy aspects, including their local and global management and organisation.
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