肉芽肿性松弛皮肤t细胞淋巴瘤表现为溃疡性和坏疽性病变,具有致命的结局:1例报告和文献复习

IF 0.2
Ruijun Su, J. Said, M. Kallen, Chayanit Jumniensuk, S. Pullarkat
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引用次数: 0

摘要

肉芽肿性松弛皮肤是一种极为罕见的皮肤t细胞淋巴瘤,通常表现为无痛性病程。临床表现为屈曲区皮肤冗余松弛,伴变异性红斑。组织学表现包括肉芽肿性t细胞浸润,弹性纤维丧失和皮肤变。在这篇文章中,我们报告了一位患有不寻常的快速进展性溃疡和坏疽性皮肤病变的患者,导致截肢并最终死亡。我们也回顾文献肉芽肿松弛皮肤具有类似侵略性的临床过程,并讨论鉴别诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Granulomatous Slack Skin T-Cell Lymphoma Manifesting as Ulcerative and Gangrenous Lesions With a Fatal Outcome: A Case Report and Review of the Literature
Granulomatous slack skin is an extremely rare cutaneous T-cell lymphoma, which often pursues an indolent disease course. Clinically, it is characterized by areas of redundant and lax skin in flexural areas, with variable erythema. Histologic findings include granulomatous T-cell infiltrates with loss of elastic fibers and poikilodermic change. In this article, we report a patient with unusual rapidly progressive ulcerative and gangrenous skin lesions, leading to amputation and ultimately demise. We also review the literature on granulomatous slack skin with similarly aggressive clinical course and discuss the differential diagnosis.
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期刊介绍: Each issue of Pathology Case Reviews examines one vital theme in the field with peer-reviewed, clinically oriented case reports that focus on diagnosis, specimen handling and reports generation. Each theme-oriented issue covers both histopathologic and cytopathologic cases, offering a comprehensive perspective that includes editorials and review articles of the newest developments in the field, differential diagnosis hints, applications of new technologies, reviews of current issues and techniques and an emphasis on new approaches.
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