Md. Anwar Hossain, S. Akhter, M. Sohrab, F. Afroz, M. Begum, Satyajit Roy Rony
{"title":"应用优化工艺提取假桑叶中抗氧化成分","authors":"Md. Anwar Hossain, S. Akhter, M. Sohrab, F. Afroz, M. Begum, Satyajit Roy Rony","doi":"10.30919/es913","DOIUrl":null,"url":null,"abstract":"In this research work, the response surface approach was constructed on a central composite design (CCD) and was applied to control optimization for antioxidant elements extraction from Justicia adhatoda shrubberies. Two extraction parameters were assessed in 14 experimental trials as methanol: water (30% to 80%) and the extraction time (4 to 6 days). The quadratic polynomial equation of multiple regression analysis forecasts the extraction process's optimization. The maximum antioxidant extract (AE) was obtained at methanol (55%) and time (6.41 days) 6.48 g/100g on trial 09. The minimum radical scavenging activity (IC 50 ) values were obtained at methanol (55%) and extraction time of 3.59 days on trial 08. It was found that the AE yields and radical scavenging activity (IC 50 ) of Justicia adhatoda leaves could be optimized at 6.62 g/100g and 1.66 μg/mL at the optimum condition at a time of 6.41 days and solvent concentration of 76.01% with overall desirability 0.96. According to the response optimizer method, the conditions that maximize the yield and minimize the DPPH are within the established restrictions. The well-fitted actual values to predicted values validate the regression model acceptability. Antioxidant properties of Justicia adhatoda leaves using response surface methodology (RSM) confirm this technique's usefulness.","PeriodicalId":36059,"journal":{"name":"Engineered Science","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Applying an Optimization Technique for the Extraction of Antioxidant Components from Justicia adhatoda Leaves\",\"authors\":\"Md. Anwar Hossain, S. Akhter, M. Sohrab, F. Afroz, M. Begum, Satyajit Roy Rony\",\"doi\":\"10.30919/es913\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this research work, the response surface approach was constructed on a central composite design (CCD) and was applied to control optimization for antioxidant elements extraction from Justicia adhatoda shrubberies. Two extraction parameters were assessed in 14 experimental trials as methanol: water (30% to 80%) and the extraction time (4 to 6 days). The quadratic polynomial equation of multiple regression analysis forecasts the extraction process's optimization. The maximum antioxidant extract (AE) was obtained at methanol (55%) and time (6.41 days) 6.48 g/100g on trial 09. The minimum radical scavenging activity (IC 50 ) values were obtained at methanol (55%) and extraction time of 3.59 days on trial 08. It was found that the AE yields and radical scavenging activity (IC 50 ) of Justicia adhatoda leaves could be optimized at 6.62 g/100g and 1.66 μg/mL at the optimum condition at a time of 6.41 days and solvent concentration of 76.01% with overall desirability 0.96. According to the response optimizer method, the conditions that maximize the yield and minimize the DPPH are within the established restrictions. The well-fitted actual values to predicted values validate the regression model acceptability. Antioxidant properties of Justicia adhatoda leaves using response surface methodology (RSM) confirm this technique's usefulness.\",\"PeriodicalId\":36059,\"journal\":{\"name\":\"Engineered Science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Engineered Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30919/es913\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Mathematics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Engineered Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30919/es913","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Mathematics","Score":null,"Total":0}
Applying an Optimization Technique for the Extraction of Antioxidant Components from Justicia adhatoda Leaves
In this research work, the response surface approach was constructed on a central composite design (CCD) and was applied to control optimization for antioxidant elements extraction from Justicia adhatoda shrubberies. Two extraction parameters were assessed in 14 experimental trials as methanol: water (30% to 80%) and the extraction time (4 to 6 days). The quadratic polynomial equation of multiple regression analysis forecasts the extraction process's optimization. The maximum antioxidant extract (AE) was obtained at methanol (55%) and time (6.41 days) 6.48 g/100g on trial 09. The minimum radical scavenging activity (IC 50 ) values were obtained at methanol (55%) and extraction time of 3.59 days on trial 08. It was found that the AE yields and radical scavenging activity (IC 50 ) of Justicia adhatoda leaves could be optimized at 6.62 g/100g and 1.66 μg/mL at the optimum condition at a time of 6.41 days and solvent concentration of 76.01% with overall desirability 0.96. According to the response optimizer method, the conditions that maximize the yield and minimize the DPPH are within the established restrictions. The well-fitted actual values to predicted values validate the regression model acceptability. Antioxidant properties of Justicia adhatoda leaves using response surface methodology (RSM) confirm this technique's usefulness.