综述:多囊卵巢疾病

Omkar A. Devade, Rohan D. Londhe, Nisarga V. Sokate, Utkarsha R. Randave, Pallavi A. Ranpise
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引用次数: 3

摘要

多囊卵巢疾病(PCOD)是育龄妇女的激素失调。PCOD患者卵巢增大,外缘有小囊肿,雄激素和雌激素的分泌速率和代谢紊乱。该综合征的病理生理是复杂的,并没有已知的单一缺陷导致,假设胰岛素抵抗是一个关键因素。鉴于PCOD患病率的增加以及相关的精神和身体问题,以及性激素变化对该病发展的影响,我们的目的是研究合成药物和草药对性激素和卵巢组织水平的影响。一些药理学研究已经描述了使用各种阿育吠陀药用植物及其成分在治疗PCOD中发挥重要作用。因此,这种药物可以通过影响卵巢形态、体重的不同激素和血清水平来部分有效地治疗这种综合征,并为研究和发现新的生物活性产品提供了机会。本文综述了几种有潜力治疗PCOD的合成药物和草药。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Review on: Polycystic Ovarian Disorder
Polycystic ovary disorder (PCOD) is hormonal disorder among reproductive-age women. Causing enlarged ovaries with small cysts on the outer edges in patients with PCOD, the secretion rate and metabolism of androgens and estrogens are disrupted. The pathophysiology of the syndrome is complex and there is no single defect from which it is known to result, it is hypothesized that insulin resistance is a key factor. With regards to the increasing prevalence of PCOD and associated mental and physical problemsas well as the effects of changes in sex hormones in development of this disease, our aim is to investigate the effects of synthetic drug and herbal drug in the serum levels of sex hormones and ovarian tissue. Several Pharmacological studies have described the use of various Ayurvedic medicinal plants and their constituents play the important role for the treatment of PCOD.Therefore, this drug can be partly effective in this syndrome via affecting the different hormones and serum levels of ovarian morphology, weight and representing an opportunity to investigate and discovery new bioactive products. This review discussed some synthetic and herbal drug which has the potential for the treatment of PCOD.
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