膀胱内灌注后的卡介苗-格林芽孢杆菌肺炎：两个病例的报告和文献综述。

IF 0.7 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Biomedical Papers-Olomouc Pub Date : 2024-06-01 Epub Date: 2023-01-02 DOI:10.5507/bp.2022.051

Martina Spisarova, Stanislav Losse, Petr Jakubec, Igor Hartmann, Milan Kral, Jiri Ehrmann, Marek Szkorupa, Hana Studentova, Bohuslav Melichar

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引用次数: 0

摘要

目的：膀胱内注射卡介苗是治疗非肌层浸润性膀胱癌的标准辅助疗法。尽管这种免疫疗法是局部性的，但仍有可能出现一些并发症：方法：我们描述了两例膀胱癌早期患者膀胱内注射卡介苗后发生全身卡介苗感染的病例：结果：两例患者均出现全身卡介苗感染，表现为卡介苗肺炎。结论：卡介苗感染是一种罕见的疾病：结论：卡介苗感染是这种治疗方法的一种罕见但潜在的严重并发症。结论：卡介苗感染是一种罕见但潜在的严重并发症，这种副作用的严重性和具体治疗方法需要及时和正确的诊断。

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Bacillus Calmette-Guérin pneumonitis after intravesical instillation: Report of two cases and a review of the literature.

Objective: Intravesical administration of bacillus Calmette-Guérin is standard adjuvant treatment of non-muscle invasive bladder cancer. In spite of the fact that this immunotherapy is locoregional, there are still risk of some complications.

Methods: We describe two cases of systemic BCG infection after intravesical administration of BCG vaccine in patients with early stage of bladder cancer.

Results: Both patients suffered from systemic BCG infection manifesting as BCG pneumonitis. After standard therapy with antituberculotic agents, both of them fully recovered.

Conclusion: BCG infection can occur as a rare but potentially serious complication of this treatment procedure. Gravity of this side effect and its specific therapy require prompt and right diagnosis.

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来源期刊

Biomedical Papers-Olomouc MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

2.30

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Biomedical Papers is a journal of Palacký University Olomouc, Faculty of Medicine and Dentistry, Olomouc, Czech Republic. It includes reviews and original articles reporting on basic and clinical research in medicine. Biomedical Papers is published as one volume per year in four issues.