纳布啡、美托咪定和阿扎哌酮用于固定化大眼的安全性和有效性

Logan F. Thomas, Chase M. Nunez, Robert O. Dittmar, R. Rech, Jack J. Richison, W. Lance, W. Cook
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引用次数: 1

摘要

摘要:在NalMed-A预混标签下,评价纳布啡(40mg /mL) +美托咪定(10mg /mL) +阿扎哌酮(10mg /mL)的安全性和有效性。从2020年1月至3月,通过飞镖枪对10只大鲵进行了7个不同采样期的固定,共记录了45次个体固定事件。NalMed-A的诱导和逆转时间分别为5.53±2.61 min和5.08±2.43 min(阿替帕唑给药后),而α -2激动剂-氯胺酮联合使用的研究中,美托咪定-氯胺酮和噻嗪-氯胺酮的中位和平均诱导时间分别为4.6 min和11.2 min。总的来说,NalMed-A在体外充分固定,经dart分娩时高热发生率为13%,死亡率为2.22%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Safety and Efficacy of Nalbuphine, Medetomidine, and Azaperone for Immobilizing Aoudad (Ammotragus lervia)
Abstract: We evaluated the safety and efficacy of nalbuphine (40 mg/mL), plus medetomidine (10 mg/mL), plus azaperone (10 mg/mL) under the premixed label NalMed-A. From January to March 2020, 10 aoudad (Ammotragus lervia) were immobilized via dart-gun for seven separate sampling periods for a total of 45 recorded individual immobilization events. Induction and reversal times with NalMed-A were 5.53±2.61 min and (following atipamezole administration) 5.08±2.43 min while previous studies with alpha-2 agonist–ketamine combinations gave median and average induction times of 4.6 min and 11.2 min using medetomidine-ketamine and xylazine-ketamine, respectively. Overall, NalMed-A adequately immobilized aoudad, with 13% incidence of hyperthermia and 2.22% mortality when delivered via dart.
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