T. Bigley, Liping Yang, L. Kang, J. Saenz, F. Victorino, W. Yokoyama
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Disruption of thymic central tolerance by infection with murine roseolovirus induces autoimmune gastritis
Bigley et al. show that neonatal murine roseolovirus infection disrupts central tolerance. Autoimmunity arises later, in the absence of ongoing infection. This study provides evidence for a new mechanism by which viruses induce autoimmunity at a time remote from initial infection.
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